Fine-tuning of antithrombotic therapy in patients with non-valvular atrial fibrillation. The AFINVA register
Objective: To determine whether antithrombotic treatment (ATT) in patients with non-valvular atrial fibrillation in a health area complies with the recommendations of current clinical guidelines. Design: Prospective observational study. Location: Primary Health Care Centres and Cardiology Department...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) |
| Repositorio: | r-FISABIO. Repositorio Institucional de Producción Científica |
| OAI Identifier: | oai:fisabio.fundanetsuite.com:p2231 |
| Acceso en línea: | https://fisabio.portalinvestigacion.com/publicaciones/2231 |
| Access Level: | acceso abierto |
| Palabra clave: | Antithrombotic treatment Oral anticoagulation Non-valvular atrial fibrillation AFINVA register |
| Sumario: | Objective: To determine whether antithrombotic treatment (ATT) in patients with non-valvular atrial fibrillation in a health area complies with the recommendations of current clinical guidelines. Design: Prospective observational study. Location: Primary Health Care Centres and Cardiology Department of a Health Department of the Valencian Community, Spain. Participants: A total of 505 patients with nonvalvular atrial fibrillation were included in the study. Main measurements: ATT was deemed to be inappropriate in patients with a CHA(2)DS(2)-VASc score >= 1 and who were not under oral anticoagulation, in patients treated with antivitamin K drugs, and poor control of oral anticoagulation, or with antiplatelet therapy inappropriately associated with anticoagulation, and in patients on ATT with a CHA(2)DS(2)-VASc score = 0. Results: The median age was 77.4 +/- 10 years. The ATT was considered inadequate in 58% of cases. Factors independently associated with inadequate ATT were age (OR: 1.02 [1-1.04]; P=.029), hypothyroidism (OR: 1.98 [1.14-3.43]; P=.015), ischaemic heart disease (OR: 1.3 [1.15-2.59]; P=.008) and paroxysmal non -valvular AF (OR: 2.11 [1.41-3.17]; P <.0001). Conclusions: These data underline the high prevalence of inadequate ATT in daily practice, as well its different causes. (C) 2017 Elsevier Espana, S.L.U. |
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