Computational modelling of the actin flow

Actin turnover plays a fundamental role in cell motility, cancer or embryogenesis. The actin flow acts as an engine for the affective motion of motile cells by means of protrusive and retractile mechanisms conditioned also by myosin motors. Different mathematical and numerical models have appeared i...

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Detalhes bibliográficos
Autor: Loosveldt Tomàs, Saskia
Formato: tesis de maestría
Fecha de publicación:2018
País:España
Recursos:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/123092
Acesso em linha:https://hdl.handle.net/2117/123092
Access Level:acceso abierto
Palavra-chave:Finite element method
cell motility
actin dynamics
finite element method
Elements finits, Mètode dels
Àrees temàtiques de la UPC::Enginyeria civil
Descrição
Resumo:Actin turnover plays a fundamental role in cell motility, cancer or embryogenesis. The actin flow acts as an engine for the affective motion of motile cells by means of protrusive and retractile mechanisms conditioned also by myosin motors. Different mathematical and numerical models have appeared in literature to model the actin flow. In this work we propose to use one of analytical models in literature to include it in a FE coupling procedure for time-dependent diffusion-convection-reaction equations governing the actin flow. Feines bàsiques: