Sensitivity of cervical cytology in endometrial cancer detection in a tertiary hospital in Spain

Introduction: Cervical cytology is a well-stablished cervical cancer screening method. However, due to the anatomical continuity of the genital tract, it can also detect signs of endometrial disease. Our aim was to estimate the sensitivity of cervical cytology in endometrial cancer detection and pro...

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Detalles Bibliográficos
Autores: Frias Gomez, Jon, Tovar, Eva, Vidal, August, Murgui, Lluis, Ibáñez, Raquel, Peremiquel Trillas, Paula, Paytubi Casabona, Sònia, Baixeras, Nuria, Zanca, Alba, Ponce i Sebastià, Jordi, Pineda, Marta, Brunet, Joan, Sanjosé Llongueras, Silvia de, Bosch, F. Xavier, Matias-Guiu, Xavier, 1958-, Alemany, Laia, Costas, Laura, Screenwide Team
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/180087
Acceso en línea:https://hdl.handle.net/2445/180087
Access Level:acceso abierto
Palabra clave:Càncer d'endometri
Citodiagnòstic
Endometrial cancer
Cytodiagnosis
Descripción
Sumario:Introduction: Cervical cytology is a well-stablished cervical cancer screening method. However, due to the anatomical continuity of the genital tract, it can also detect signs of endometrial disease. Our aim was to estimate the sensitivity of cervical cytology in endometrial cancer detection and prognosis in a large population over a 30-year period in a large academic tertiary hospital in Spain. Methodology: We performed a search for women diagnosed with endometrial cancer from 1990 to 2020, who were surgically treated and had a previous cervical cytology result. Information Technologies Department databases from Bellvitge University Hospital and the Screenwide case-control study's database were used. Cervical cytology results were classified as abnormal when squamous lesions, glandular atypia or malignant cells were identified. Results: Overall, we evaluated 371 women with endometrial cancer and a documented cervical cytology performed within 3 years previous to surgical treatment. Overall, the sensitivity of cervical cytology for endometrial cancer detection was 25.6%. Several clinico-pathological characteristics, such as non-endometrioid histology and a higher stage, were correlated with higher sensitivity.