Tunnels for protein export from the endoplasmic reticulum

The functions of coat protein complex II (COPII) coats in cargo packaging and the creation of vesicles at the endoplasmic reticulum are conserved in eukaryotic protein secretion. Standard COPII vesicles, however, cannot handle the secretion of metazoan-specific cargoes such as procollagens, apolipop...

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Detalles Bibliográficos
Autores: Raote, Ishier, Malhotra, Vivek
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2021
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/47377
Acceso en línea:http://hdl.handle.net/10230/47377
http://dx.doi.org/10.1146/annurev-biochem-080120-022017
Access Level:acceso abierto
Palabra clave:Proteïnes
Reticle endoplasmàtic
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spelling Tunnels for protein export from the endoplasmic reticulumRaote, IshierMalhotra, VivekProteïnesReticle endoplasmàticThe functions of coat protein complex II (COPII) coats in cargo packaging and the creation of vesicles at the endoplasmic reticulum are conserved in eukaryotic protein secretion. Standard COPII vesicles, however, cannot handle the secretion of metazoan-specific cargoes such as procollagens, apolipoproteins, and mucins. Metazoans have thus evolved modules centered on proteins like TANGO1 (transport and Golgi organization 1) to engage COPII coats and early secretory pathway membranes to engineer a novel mode of cargo export at the endoplasmic reticulum.Financial support from: Ministerio de Economía y Competitividad (SEV-2012-0208, BFU2013-44188-P, and CSD2009-00016 to V.M. and IJCI-2017-34751 to I.R.)Annual Reviews Inc20212021info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/47377http://dx.doi.org/10.1146/annurev-biochem-080120-022017reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésAnnu Rev Biochem. 2021;90:605-30info:eu-repo/grantAgreement/ES/3PN/CSD2009-00016info:eu-repo/grantAgreement/ES/1PE/BFU2013-44188-Pinfo:eu-repo/grantAgreement/ES/2PE/IJCI-2017-34751© Annual Reviews. Posted, with permission, from the Annual Review of Biochemistry, 2021;90:605-30.info:eu-repo/semantics/openAccessoai:recercat.cat:10230/473772026-05-29T05:05:01Z
dc.title.none.fl_str_mv Tunnels for protein export from the endoplasmic reticulum
title Tunnels for protein export from the endoplasmic reticulum
spellingShingle Tunnels for protein export from the endoplasmic reticulum
Raote, Ishier
Proteïnes
Reticle endoplasmàtic
title_short Tunnels for protein export from the endoplasmic reticulum
title_full Tunnels for protein export from the endoplasmic reticulum
title_fullStr Tunnels for protein export from the endoplasmic reticulum
title_full_unstemmed Tunnels for protein export from the endoplasmic reticulum
title_sort Tunnels for protein export from the endoplasmic reticulum
dc.creator.none.fl_str_mv Raote, Ishier
Malhotra, Vivek
author Raote, Ishier
author_facet Raote, Ishier
Malhotra, Vivek
author_role author
author2 Malhotra, Vivek
author2_role author
dc.subject.none.fl_str_mv Proteïnes
Reticle endoplasmàtic
topic Proteïnes
Reticle endoplasmàtic
description The functions of coat protein complex II (COPII) coats in cargo packaging and the creation of vesicles at the endoplasmic reticulum are conserved in eukaryotic protein secretion. Standard COPII vesicles, however, cannot handle the secretion of metazoan-specific cargoes such as procollagens, apolipoproteins, and mucins. Metazoans have thus evolved modules centered on proteins like TANGO1 (transport and Golgi organization 1) to engage COPII coats and early secretory pathway membranes to engineer a novel mode of cargo export at the endoplasmic reticulum.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/47377
http://dx.doi.org/10.1146/annurev-biochem-080120-022017
url http://hdl.handle.net/10230/47377
http://dx.doi.org/10.1146/annurev-biochem-080120-022017
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Annu Rev Biochem. 2021;90:605-30
info:eu-repo/grantAgreement/ES/3PN/CSD2009-00016
info:eu-repo/grantAgreement/ES/1PE/BFU2013-44188-P
info:eu-repo/grantAgreement/ES/2PE/IJCI-2017-34751
dc.rights.none.fl_str_mv © Annual Reviews. Posted, with permission, from the Annual Review of Biochemistry, 2021;90:605-30.
info:eu-repo/semantics/openAccess
rights_invalid_str_mv © Annual Reviews. Posted, with permission, from the Annual Review of Biochemistry, 2021;90:605-30.
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Annual Reviews Inc
publisher.none.fl_str_mv Annual Reviews Inc
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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