Relevancia de la fibrilación auricular en la endocarditis infecciosa

Atrial fibrillation (AF) is the most common cardiac arrhythmia in adults and has been independently related to increased morbidity and mortality. In particular, AF has been associated with complications such as ischemic stroke, and heart failure. It is also well known the association between new-ons...

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Detalles Bibliográficos
Autor: Ferrera Durán, Carlos
Tipo de recurso: tesis doctoral
Fecha de publicación:2017
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:español
OAI Identifier:oai:docta.ucm.es:20.500.14352/21848
Acceso en línea:https://hdl.handle.net/20.500.14352/21848
Access Level:acceso abierto
Palabra clave:616.126-002(043.2)
Endocarditis
Fibrilación auricular
Atrial fibrillation
Cardiología
Microbiología médica
3205.01 Cardiología
3201.03 Microbiología Clínica
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spelling Relevancia de la fibrilación auricular en la endocarditis infecciosaFerrera Durán, Carlos616.126-002(043.2)EndocarditisFibrilación auricularAtrial fibrillationCardiologíaMicrobiología médica3205.01 Cardiología3201.03 Microbiología ClínicaAtrial fibrillation (AF) is the most common cardiac arrhythmia in adults and has been independently related to increased morbidity and mortality. In particular, AF has been associated with complications such as ischemic stroke, and heart failure. It is also well known the association between new-onset atrial fibrillation (NAF) and mortality in patients hospitalized with severe sepsis or heart failure. Infective endocarditis (IE) is a severe infectious disease producing a great systemic inflammatory reaction and local valve destruction leading to severe hemodynamic changes. Not surprisingly, AF is common in IE, sometimes co-existing with heart failure and systemic embolism. Nevertheless, there are no data on how AF affects the clinical outcome of patients with IE. Hypothesis 1. Development of NAF during the active phase of IE would have prognostic implications. Patients with IE and NAF have a worse clinical outcome than those who remain in sinus rhythm. 2. Patients with NAF might be particularly prone to congestive heart failure and thrombo-embolic events. Objectives 1. To investigate patient characteristics, microbiology, and echocardiographic findings of episodes with IE and NAF. We further aim to compare the in-hospital course and prognosis of patients who develop de novo AF with that of those who remained in sinus rhythm or had previous AF. 2. To study the clinical course and in-hospital events of patients with IE from each group. 3. To estimate the potential effect of NAF over in-hospital prognosis and mortality. 4. To evaluate the clinical impact of AF (new-onset and previous AF) over the risk of heart failure and systemic embolism in patients with IE. 5. To explore interactions between NAF and heart failure in IE and its prognostic impact over in-hospital mortality of patients with IE...Universidad Complutense de MadridMacaya Miguel, CarlosVilacosta, IsidreUniversidad Complutense de Madrid20172017-02-2120172017-02-21doctoral thesishttp://purl.org/coar/resource_type/c_db06info:eu-repo/semantics/doctoralThesisapplication/pdfhttps://hdl.handle.net/20.500.14352/21848reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Españolspaopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/218482026-06-02T12:44:21Z
dc.title.none.fl_str_mv Relevancia de la fibrilación auricular en la endocarditis infecciosa
title Relevancia de la fibrilación auricular en la endocarditis infecciosa
spellingShingle Relevancia de la fibrilación auricular en la endocarditis infecciosa
Ferrera Durán, Carlos
616.126-002(043.2)
Endocarditis
Fibrilación auricular
Atrial fibrillation
Cardiología
Microbiología médica
3205.01 Cardiología
3201.03 Microbiología Clínica
title_short Relevancia de la fibrilación auricular en la endocarditis infecciosa
title_full Relevancia de la fibrilación auricular en la endocarditis infecciosa
title_fullStr Relevancia de la fibrilación auricular en la endocarditis infecciosa
title_full_unstemmed Relevancia de la fibrilación auricular en la endocarditis infecciosa
title_sort Relevancia de la fibrilación auricular en la endocarditis infecciosa
dc.creator.none.fl_str_mv Ferrera Durán, Carlos
author Ferrera Durán, Carlos
author_facet Ferrera Durán, Carlos
author_role author
dc.contributor.none.fl_str_mv Macaya Miguel, Carlos
Vilacosta, Isidre
Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 616.126-002(043.2)
Endocarditis
Fibrilación auricular
Atrial fibrillation
Cardiología
Microbiología médica
3205.01 Cardiología
3201.03 Microbiología Clínica
topic 616.126-002(043.2)
Endocarditis
Fibrilación auricular
Atrial fibrillation
Cardiología
Microbiología médica
3205.01 Cardiología
3201.03 Microbiología Clínica
description Atrial fibrillation (AF) is the most common cardiac arrhythmia in adults and has been independently related to increased morbidity and mortality. In particular, AF has been associated with complications such as ischemic stroke, and heart failure. It is also well known the association between new-onset atrial fibrillation (NAF) and mortality in patients hospitalized with severe sepsis or heart failure. Infective endocarditis (IE) is a severe infectious disease producing a great systemic inflammatory reaction and local valve destruction leading to severe hemodynamic changes. Not surprisingly, AF is common in IE, sometimes co-existing with heart failure and systemic embolism. Nevertheless, there are no data on how AF affects the clinical outcome of patients with IE. Hypothesis 1. Development of NAF during the active phase of IE would have prognostic implications. Patients with IE and NAF have a worse clinical outcome than those who remain in sinus rhythm. 2. Patients with NAF might be particularly prone to congestive heart failure and thrombo-embolic events. Objectives 1. To investigate patient characteristics, microbiology, and echocardiographic findings of episodes with IE and NAF. We further aim to compare the in-hospital course and prognosis of patients who develop de novo AF with that of those who remained in sinus rhythm or had previous AF. 2. To study the clinical course and in-hospital events of patients with IE from each group. 3. To estimate the potential effect of NAF over in-hospital prognosis and mortality. 4. To evaluate the clinical impact of AF (new-onset and previous AF) over the risk of heart failure and systemic embolism in patients with IE. 5. To explore interactions between NAF and heart failure in IE and its prognostic impact over in-hospital mortality of patients with IE...
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-02-21
2017
2017-02-21
dc.type.none.fl_str_mv doctoral thesis
http://purl.org/coar/resource_type/c_db06
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dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/21848
url https://hdl.handle.net/20.500.14352/21848
dc.language.none.fl_str_mv Español
spa
language_invalid_str_mv Español
language spa
dc.rights.none.fl_str_mv open access
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dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Complutense de Madrid
publisher.none.fl_str_mv Universidad Complutense de Madrid
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
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