Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat

[EN]The current study was performed to analyse the potential existence and structure of a GHRH-transporting tuberoinfundibular system in the rat median eminence. The immunocytochemical analysis using anti-GHRH revealed an intense immunoreaction in the ependimary cells, tanycytes, at the level of the...

Descripción completa

Detalles Bibliográficos
Autores: Carretero González, José, Burks, Deborah, Rubio, Manuel, Blanco Barco, Enrique José, Herrero, Julio J., Bodego, Pilar, Juanes Méndez, Juan Antonio, Hernández, Elena, Riesco-López, José M.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2002
País:España
Institución:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/158099
Acceso en línea:http://hdl.handle.net/10366/158099
Access Level:acceso abierto
Palabra clave:Hypothalamus
Neuropeptides
Ependimary cells
Immunocytochemistry
Colchicine
id ES_9c158eaa140a8cdc00aeec2a1fca8f06
oai_identifier_str oai:gredos.usal.es:10366/158099
network_acronym_str ES
network_name_str España
repository_id_str
spelling Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the ratCarretero González, JoséBurks, DeborahRubio, ManuelBlanco Barco, Enrique JoséHerrero, Julio J.Bodego, PilarJuanes Méndez, Juan AntonioHernández, ElenaRiesco-López, José M.HypothalamusNeuropeptidesEpendimary cellsImmunocytochemistryColchicine[EN]The current study was performed to analyse the potential existence and structure of a GHRH-transporting tuberoinfundibular system in the rat median eminence. The immunocytochemical analysis using anti-GHRH revealed an intense immunoreaction in the ependimary cells, tanycytes, at the level of the floor of the infundibular recess forming part of the median eminence. The basal processes of these cells course towards the external layer of the median eminence and reach the growth hormone-releasing hormone (GHRH) fibres of the tuberoinfundibular tract and this reaction was increased after intraventricular treatment with colchicine. Thus, these observations suggest the existence of a second or alternative cerebrospinal fluid-mediated route of GHRH transport to the median eminence and implicate the involvement of tanycytes in the regulation of this novel transport system.202420242002info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10366/158099reponame:GREDOS. Repositorio Institucional de la Universidad de Salamancainstname:Universidad de Salamanca (USAL)InglésAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:gredos.usal.es:10366/1580992026-06-07T06:28:51Z
dc.title.none.fl_str_mv Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat
title Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat
spellingShingle Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat
Carretero González, José
Hypothalamus
Neuropeptides
Ependimary cells
Immunocytochemistry
Colchicine
title_short Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat
title_full Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat
title_fullStr Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat
title_full_unstemmed Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat
title_sort Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat
dc.creator.none.fl_str_mv Carretero González, José
Burks, Deborah
Rubio, Manuel
Blanco Barco, Enrique José
Herrero, Julio J.
Bodego, Pilar
Juanes Méndez, Juan Antonio
Hernández, Elena
Riesco-López, José M.
author Carretero González, José
author_facet Carretero González, José
Burks, Deborah
Rubio, Manuel
Blanco Barco, Enrique José
Herrero, Julio J.
Bodego, Pilar
Juanes Méndez, Juan Antonio
Hernández, Elena
Riesco-López, José M.
author_role author
author2 Burks, Deborah
Rubio, Manuel
Blanco Barco, Enrique José
Herrero, Julio J.
Bodego, Pilar
Juanes Méndez, Juan Antonio
Hernández, Elena
Riesco-López, José M.
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Hypothalamus
Neuropeptides
Ependimary cells
Immunocytochemistry
Colchicine
topic Hypothalamus
Neuropeptides
Ependimary cells
Immunocytochemistry
Colchicine
description [EN]The current study was performed to analyse the potential existence and structure of a GHRH-transporting tuberoinfundibular system in the rat median eminence. The immunocytochemical analysis using anti-GHRH revealed an intense immunoreaction in the ependimary cells, tanycytes, at the level of the floor of the infundibular recess forming part of the median eminence. The basal processes of these cells course towards the external layer of the median eminence and reach the growth hormone-releasing hormone (GHRH) fibres of the tuberoinfundibular tract and this reaction was increased after intraventricular treatment with colchicine. Thus, these observations suggest the existence of a second or alternative cerebrospinal fluid-mediated route of GHRH transport to the median eminence and implicate the involvement of tanycytes in the regulation of this novel transport system.
publishDate 2002
dc.date.none.fl_str_mv 2002
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10366/158099
url http://hdl.handle.net/10366/158099
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname:Universidad de Salamanca (USAL)
instname_str Universidad de Salamanca (USAL)
reponame_str GREDOS. Repositorio Institucional de la Universidad de Salamanca
collection GREDOS. Repositorio Institucional de la Universidad de Salamanca
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869414627123658752
score 15,811543

Similares en LA Referencia