Convergence and Numerical Solution of a Model for Tumor Growth

n this paper, we show the application of the meshless numerical method called “Generalized Finite Diference Method” (GFDM) for solving a model for tumor growth with nutrient density, extracellular matrix and matrix degrading enzymes, [recently proposed by Li and Hu]. We derive the discretization of...

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Detalles Bibliográficos
Autores: Benito, Juan J., García, Ángel, Gavete, María Lucía, Negreanu Pruna, Mihaela, Ureña, Francisco, Vargas, Antonio M.
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/7345
Acceso en línea:https://hdl.handle.net/20.500.14352/7345
Access Level:acceso abierto
Palabra clave:517
Generalized finite difference method
Meshless numerical method
Numerical convergence
Tumor growth
Parabolic-hyperbolic system
Análisis matemático
1202 Análisis y Análisis Funcional
Descripción
Sumario:n this paper, we show the application of the meshless numerical method called “Generalized Finite Diference Method” (GFDM) for solving a model for tumor growth with nutrient density, extracellular matrix and matrix degrading enzymes, [recently proposed by Li and Hu]. We derive the discretization of the parabolic–hyperbolic–parabolic–elliptic system by means of the explicit formulae of the GFDM. We provide a theoretical proof of the convergence of the spatial–temporal scheme to the continuous solution and we show several examples over regular and irregular distribution of points. This shows the feasibility of the method for solving this nonlinear model appearing in Biology and Medicine in complicated and realistic domains.