Exercise and Childhood Cancer-A Historical Review

Childhood cancer survivors are at risk of developing important adverse effects, many of which persist for years after the end of treatment. The implementation of interventions aiming at attenuating tumor/treatment-associated adverse effects is therefore a major issue in pediatric oncology, and there...

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Detalhes bibliográficos
Autores: Morales Rojas, Javier Salvador, Valenzuela Tallón, Pedro Luis, Velázquez Díaz, Daniel, Castillo García, Adrián, Jiménez Pavón, David, Lucía Mulas, Alejandro, Fiuza Luces, María del Carmen
Formato: artículo
Fecha de publicación:2021
País:España
Recursos:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/11303
Acesso em linha:http://hdl.handle.net/11268/11303
Access Level:acceso abierto
Palavra-chave:Ejercicio físico
Terapia por ejercicio
Células madre
Cáncer
Niño
Deporte
Descrição
Resumo:Childhood cancer survivors are at risk of developing important adverse effects, many of which persist for years after the end of treatment. The implementation of interventions aiming at attenuating tumor/treatment-associated adverse effects is therefore a major issue in pediatric oncology, and there is growing evidence that physical exercise could help in this regard. The present review aims to summarize the main milestones achieved in pediatric exercise oncology. For this purpose, we conducted a systematic review of relevant studies written in English in the electronic database PubMed (from inception to 14 August 2021). This review traces the field of pediatric exercise oncology throughout recent history based on three fundamental pillars: (i) exercise during childhood cancer treatment; (ii) exercise during/after hematopoietic stem cell transplantation; and (iii) exercise after childhood cancer treatment. Accumulating evidence--although still preliminary in many cases--supports the safety and potential benefits of regular exercise (with no major contraindications in general) in the childhood cancer continuum, even during the most aggressive phases of treatment. Exercise can indeed represent an effective coadjuvant therapy for attenuating cancer-related adverse effects.