Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease

Background: Parkinson’s disease (PD) is a chronic neurodegenerative disease that implies a progressive and invalidating functional organic disorder, which continues to evolve till the end of life and causes different mental and physical alterations that influence the quality of life of those affecte...

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Autores: Candel Parra, Eduardo, Córcoles Jiménez, Pilar, Delicado Useros, Victoria, Hernández Martínez, Antonio, Molina Alarcón, Milagros
Formato: artículo
Fecha de publicación:2021
País:España
Recursos:Universidad de Castilla-La Mancha
Repositorio:RUIdeRA. Repositorio Institucional de la UCLM
OAI Identifier:oai:ruidera.uclm.es:10578/46893
Acesso em linha:https://hdl.handle.net/10578/46893
Access Level:acceso abierto
Palavra-chave:Motor symptoms
Nonmotor symptoms
Parkinson’s disease
PDQ-39
Quality of life
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spelling Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s DiseaseCandel Parra, EduardoCórcoles Jiménez, PilarDelicado Useros, VictoriaHernández Martínez, AntonioMolina Alarcón, MilagrosMotor symptomsNonmotor symptomsParkinson’s diseasePDQ-39Quality of lifeBackground: Parkinson’s disease (PD) is a chronic neurodegenerative disease that implies a progressive and invalidating functional organic disorder, which continues to evolve till the end of life and causes different mental and physical alterations that influence the quality of life of those affected. Objective: To determine the relationship between motor and nonmotor symptoms and the quality of life of persons with PD. Methods: An analytic, descriptive, cross-sectional study was conducted with patients with different degrees of PD in the Albacete Health district. The estimated sample size required was 155 patients. The instruments used for data collection included a purpose-designed questionnaire and “Parkinson’s Disease Questionnaire” (PDQ-39), which measures eight dimensions and has a global index where a higher score indicates a worse quality of life. A descriptive and bivariate analysis was conducted (SPSS® IBM 24.0). Ethical aspects: informed consent and anonymized data. Results: A strong correlation was found between the number of motor and nonmotor symptoms and global health-related quality of life and the domains mobility, activities of daily living, emotional well-being, cognitive status, and pain (p < 0.05). Receiving pharmacological treatment and taking more than four medicines per day was significantly associated with a worse quality of life (p < 0.05). Patients who had undergone surgical treatment did not show better global quality of life (p = 0.076). Conclusions: All nonmotor symptoms and polypharmacy were significantly associated with a worse global quality of lifeMDPI202620262021info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://hdl.handle.net/10578/46893reponame:RUIdeRA. Repositorio Institucional de la UCLMinstname:Universidad de Castilla-La ManchaInglésinfo:eu-repo/semantics/openAccessoai:ruidera.uclm.es:10578/468932026-05-27T07:36:41Z
dc.title.none.fl_str_mv Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease
title Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease
spellingShingle Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease
Candel Parra, Eduardo
Motor symptoms
Nonmotor symptoms
Parkinson’s disease
PDQ-39
Quality of life
title_short Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease
title_full Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease
title_fullStr Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease
title_full_unstemmed Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease
title_sort Relationship between Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson’s Disease
dc.creator.none.fl_str_mv Candel Parra, Eduardo
Córcoles Jiménez, Pilar
Delicado Useros, Victoria
Hernández Martínez, Antonio
Molina Alarcón, Milagros
author Candel Parra, Eduardo
author_facet Candel Parra, Eduardo
Córcoles Jiménez, Pilar
Delicado Useros, Victoria
Hernández Martínez, Antonio
Molina Alarcón, Milagros
author_role author
author2 Córcoles Jiménez, Pilar
Delicado Useros, Victoria
Hernández Martínez, Antonio
Molina Alarcón, Milagros
author2_role author
author
author
author
dc.subject.none.fl_str_mv Motor symptoms
Nonmotor symptoms
Parkinson’s disease
PDQ-39
Quality of life
topic Motor symptoms
Nonmotor symptoms
Parkinson’s disease
PDQ-39
Quality of life
description Background: Parkinson’s disease (PD) is a chronic neurodegenerative disease that implies a progressive and invalidating functional organic disorder, which continues to evolve till the end of life and causes different mental and physical alterations that influence the quality of life of those affected. Objective: To determine the relationship between motor and nonmotor symptoms and the quality of life of persons with PD. Methods: An analytic, descriptive, cross-sectional study was conducted with patients with different degrees of PD in the Albacete Health district. The estimated sample size required was 155 patients. The instruments used for data collection included a purpose-designed questionnaire and “Parkinson’s Disease Questionnaire” (PDQ-39), which measures eight dimensions and has a global index where a higher score indicates a worse quality of life. A descriptive and bivariate analysis was conducted (SPSS® IBM 24.0). Ethical aspects: informed consent and anonymized data. Results: A strong correlation was found between the number of motor and nonmotor symptoms and global health-related quality of life and the domains mobility, activities of daily living, emotional well-being, cognitive status, and pain (p < 0.05). Receiving pharmacological treatment and taking more than four medicines per day was significantly associated with a worse quality of life (p < 0.05). Patients who had undergone surgical treatment did not show better global quality of life (p = 0.076). Conclusions: All nonmotor symptoms and polypharmacy were significantly associated with a worse global quality of life
publishDate 2021
dc.date.none.fl_str_mv 2021
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10578/46893
url https://hdl.handle.net/10578/46893
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:RUIdeRA. Repositorio Institucional de la UCLM
instname:Universidad de Castilla-La Mancha
instname_str Universidad de Castilla-La Mancha
reponame_str RUIdeRA. Repositorio Institucional de la UCLM
collection RUIdeRA. Repositorio Institucional de la UCLM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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