Coenzyme Q10 supplementation: Efficacy, safety, and formulation challenges

World population growth and aging are posing unprecedented challenges in sus-taining the health of 9.1 billion people that will be occupying the planet by 2050.Although noncommunicable diseases such as cardiovascular and neurodegenerativediseases, cancer, and diabetes are among the top 10 global cau...

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Detalhes bibliográficos
Autores: Arenas Jal, Marta, Suñé i Negre, Josep M. (Josep Maria), García Montoya, Encarna
Tipo de documento: artigo
Estado:Versión aceptada para publicación
Data de publicação:2020
País:España
Recursos:Universidad de Barcelona
Repositório:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/181270
Acesso em linha:https://hdl.handle.net/2445/181270
Access Level:Acceso aberto
Palavra-chave:Coenzims
Suplements nutritius
Administració de medicaments
Coenzymes
Dietary supplements
Administration of drugs
Descrição
Resumo:World population growth and aging are posing unprecedented challenges in sus-taining the health of 9.1 billion people that will be occupying the planet by 2050.Although noncommunicable diseases such as cardiovascular and neurodegenerativediseases, cancer, and diabetes are among the top 10 global causes of death, they canbe prevented by risk factor reduction, early detection, and adequate treatment. Sincea healthy diet along with dietary supplementation could play an important role toreduce morbidity and cut off its associated health care costs, research in the food andnutrition area is required to find solutions to global challenges affecting health. As a result of the healthy living trend, dietary supplements category is growing fast,leading to an urgent need for dietitians, physicians, and policy makers to broaden thescientific evidence on the efficacy and safety of a wide range of active ingredients.Coenzyme Q10 (CoQ10), as the third most consumed dietary supplement, and as apotential candidate for the treatment of various noncommunicable diseases that areamong the global top 10 causes of death, has gained interest over years. Scientificevidence regarding mainly CoQ10 efficacy and safety, as well as formulationchallenges, is addressed in this review.