Improved synthesis of pyrrolo[1,2-c]pyrimidine and derivatives
An improved synthesis of pyrrolo[1,2-c]pyrimidine derivatives by cyclocondensation of pyrrole-2-carboxaldehydes with tosylmethyl isocyanide followed by desulfonylation of the resulting 2-tosylpyrrolo[1,2-c]pyrimidines with sodium amalgam is described.
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 1996 |
| País: | España |
| Institución: | Universidad de Alcalá (UAH) |
| Repositorio: | e_Buah Biblioteca Digital Universidad de Alcalá |
| Idioma: | inglés |
| OAI Identifier: | oai:ebuah.uah.es:10017/3427 |
| Acceso en línea: | http://hdl.handle.net/10017/3427 https://dx.doi.org/10.1016/0040-4039(96)00812-X |
| Access Level: | acceso abierto |
| Palabra clave: | Pyrrolo[1,2-c]pyrimidine Ciencia Química orgánica Science Chemistry, organic |
| Sumario: | An improved synthesis of pyrrolo[1,2-c]pyrimidine derivatives by cyclocondensation of pyrrole-2-carboxaldehydes with tosylmethyl isocyanide followed by desulfonylation of the resulting 2-tosylpyrrolo[1,2-c]pyrimidines with sodium amalgam is described. |
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