Fabrication of Gelatin/Bioactive Glass Hybrid Scaffolds for Bone Tissue- Engineering
In this work, hybrid scaffold materials composed of gelatin and Bioactive Glass (BG) have been fabricated. BG particulates in the ternary system SiO2 − CaO − P 2 O 5 have been synthesized initially using the sol-gel method. The gelatin/BG scaffolds were shaped by a freeze-drying process obtaining ho...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2014 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/104316 |
| Acceso en línea: | http://hdl.handle.net/10261/104316 |
| Access Level: | acceso abierto |
| Palabra clave: | Gelatin Bioactive glasses Bone tissue engineering Macroporous scaffold |
| Sumario: | In this work, hybrid scaffold materials composed of gelatin and Bioactive Glass (BG) have been fabricated. BG particulates in the ternary system SiO2 − CaO − P 2 O 5 have been synthesized initially using the sol-gel method. The gelatin/BG scaffolds were shaped by a freeze-drying process obtaining homogeneous and reproducible final macroporous structures. BG particulates precursor and the final hybrid macroporous structures (scaffolds) were characterized using Field Emission Scanning Electron Microscopy (FE-SEM), Energy Dispersive X-ray Analysis (EDX), X-ray diffraction (XRD) and thermal analysis. Finally, the scaffolds were essayed in Simulated Body Fluid (SBF) in vitro showing a bioactive response. |
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