Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms

Arsenic (As) is quite an abundant metalloid, with ancient origin and ubiquitous distribution, which represents a severe environmental risk and a global problem for public health. Microbial exposure to As compounds in the environment has happened since the beginning of time. Selective pressure has in...

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Detalles Bibliográficos
Autores: De Francisco, Patricia, Martín González, Ana María, Rodriguez Martín, Daniel, Díaz del Toro, Silvia
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/4779
Acceso en línea:https://hdl.handle.net/20.500.14352/4779
Access Level:acceso abierto
Palabra clave:593.17
579.25
546.19
Arsenic
Toxicity
Yeasts
Microalgae
Resistance mechanisms
Toxicología (Medicina)
Microbiología (Biología)
3214 Toxicología
2414 Microbiología
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oai_identifier_str oai:docta.ucm.es:20.500.14352/4779
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network_name_str España
repository_id_str
spelling Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic MicroorganismsDe Francisco, PatriciaMartín González, Ana MaríaRodriguez Martín, DanielDíaz del Toro, Silvia593.17579.25546.19ArsenicToxicityYeastsMicroalgaeResistance mechanismsToxicología (Medicina)Microbiología (Biología)3214 Toxicología2414 MicrobiologíaArsenic (As) is quite an abundant metalloid, with ancient origin and ubiquitous distribution, which represents a severe environmental risk and a global problem for public health. Microbial exposure to As compounds in the environment has happened since the beginning of time. Selective pressure has induced the evolution of various genetic systems conferring useful capacities in many microorganisms to detoxify and even use arsenic, as an energy source. This review summarizes the microbial impact of the As biogeochemical cycle. Moreover, the poorly known adverse effects of this element on eukaryotic microbes, as well as the As uptake and detoxification mechanisms developed by yeast and protists, are discussed. Finally, an outlook of As microbial remediation makes evident the knowledge gaps and the necessity of new approaches to mitigate this environmental challenge.MPDIUniversidad Complutense de Madrid20212021-11-1720212021-11-17journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/4779reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/47792026-06-02T12:44:21Z
dc.title.none.fl_str_mv Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
spellingShingle Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
De Francisco, Patricia
593.17
579.25
546.19
Arsenic
Toxicity
Yeasts
Microalgae
Resistance mechanisms
Toxicología (Medicina)
Microbiología (Biología)
3214 Toxicología
2414 Microbiología
title_short Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title_full Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title_fullStr Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title_full_unstemmed Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
title_sort Interactions with Arsenic: Mechanisms of Toxicity and Cellular Resistance in Eukaryotic Microorganisms
dc.creator.none.fl_str_mv De Francisco, Patricia
Martín González, Ana María
Rodriguez Martín, Daniel
Díaz del Toro, Silvia
author De Francisco, Patricia
author_facet De Francisco, Patricia
Martín González, Ana María
Rodriguez Martín, Daniel
Díaz del Toro, Silvia
author_role author
author2 Martín González, Ana María
Rodriguez Martín, Daniel
Díaz del Toro, Silvia
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 593.17
579.25
546.19
Arsenic
Toxicity
Yeasts
Microalgae
Resistance mechanisms
Toxicología (Medicina)
Microbiología (Biología)
3214 Toxicología
2414 Microbiología
topic 593.17
579.25
546.19
Arsenic
Toxicity
Yeasts
Microalgae
Resistance mechanisms
Toxicología (Medicina)
Microbiología (Biología)
3214 Toxicología
2414 Microbiología
description Arsenic (As) is quite an abundant metalloid, with ancient origin and ubiquitous distribution, which represents a severe environmental risk and a global problem for public health. Microbial exposure to As compounds in the environment has happened since the beginning of time. Selective pressure has induced the evolution of various genetic systems conferring useful capacities in many microorganisms to detoxify and even use arsenic, as an energy source. This review summarizes the microbial impact of the As biogeochemical cycle. Moreover, the poorly known adverse effects of this element on eukaryotic microbes, as well as the As uptake and detoxification mechanisms developed by yeast and protists, are discussed. Finally, an outlook of As microbial remediation makes evident the knowledge gaps and the necessity of new approaches to mitigate this environmental challenge.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-11-17
2021
2021-11-17
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/4779
url https://hdl.handle.net/20.500.14352/4779
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MPDI
publisher.none.fl_str_mv MPDI
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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