Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloon

Background: Intracranial atherosclerotic disease is an important cause of ischemic stroke due to large vessel occlusion. The acute management of these occlusions is challenging and associates an important risk of complications, especially when mechanical thrombectomy does not achieve vessel recanali...

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Autores: Serrano, BS, Fernandez, FH, Hernandez, NL, Soler, EE, Barbieri, G, Nuevo, JDM
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Recursos:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
Repositorio:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
OAI Identifier:oai:isabial.fundanetsuite.com:p6500
Acesso em linha:https://isabial.portalinvestigacion.com/publicaciones6500
Access Level:acceso abierto
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repository_id_str
spelling Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloonSerrano, BSFernandez, FHHernandez, NLSoler, EEBarbieri, GNuevo, JDMBackground: Intracranial atherosclerotic disease is an important cause of ischemic stroke due to large vessel occlusion. The acute management of these occlusions is challenging and associates an important risk of complications, especially when mechanical thrombectomy does not achieve vessel recanalization. In this context, the ELUTAX "3 '' drug-eluting balloon has been designed for neurological procedures. Nevertheless, there is not enough clinical evidence of this balloon. We report our experience with ELUTAX "3 '' during mechanical thrombectomy, explaining the technical details and the outcome of the procedure, the subsequent management and the clinical evolution of the patients. Methods: We report four cases of patients with acute stroke due to intracranial atherosclerosis who were treated with the Elutax "3 '' drug-eluting-balloon. Results: Using the Elutax "3 '' we achieved a complete recovery of the occluded arteries caliber (mTICI 3) and a good performance status of our patients on discharge, with the only remarkable complication of a mild asymptomatic subarachnoid bleeding in one of them. The 90-days mRS in those patients was less or equal than 2, and they have not experienced recurrence of the strokes in the long term follow-up. Conclusions: In our experience, the Elutax "3 '' might be a safe and effective therapeutic option in acute large vessel occlusion secondary to intracranial atherosclerotic disease. However, further studies will be necessary to evaluate the efficacy and safety of this device.ELSEVIER2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://isabial.portalinvestigacion.com/publicaciones6500Interdisciplinary Neurosurgery-Advanced Techniques and Case ManagementISSN: 22147519reponame:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicanteinstname:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)Inglésinfo:eu-repo/semantics/openAccessoai:isabial.fundanetsuite.com:p65002026-06-12T10:20:37Z
dc.title.none.fl_str_mv Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloon
title Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloon
spellingShingle Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloon
Serrano, BS
title_short Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloon
title_full Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloon
title_fullStr Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloon
title_full_unstemmed Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloon
title_sort Treatment of acute occlusion due to intracranial atherosclerosis by with ELUTAX "3 '' drug-eluting balloon
dc.creator.none.fl_str_mv Serrano, BS
Fernandez, FH
Hernandez, NL
Soler, EE
Barbieri, G
Nuevo, JDM
author Serrano, BS
author_facet Serrano, BS
Fernandez, FH
Hernandez, NL
Soler, EE
Barbieri, G
Nuevo, JDM
author_role author
author2 Fernandez, FH
Hernandez, NL
Soler, EE
Barbieri, G
Nuevo, JDM
author2_role author
author
author
author
author
description Background: Intracranial atherosclerotic disease is an important cause of ischemic stroke due to large vessel occlusion. The acute management of these occlusions is challenging and associates an important risk of complications, especially when mechanical thrombectomy does not achieve vessel recanalization. In this context, the ELUTAX "3 '' drug-eluting balloon has been designed for neurological procedures. Nevertheless, there is not enough clinical evidence of this balloon. We report our experience with ELUTAX "3 '' during mechanical thrombectomy, explaining the technical details and the outcome of the procedure, the subsequent management and the clinical evolution of the patients. Methods: We report four cases of patients with acute stroke due to intracranial atherosclerosis who were treated with the Elutax "3 '' drug-eluting-balloon. Results: Using the Elutax "3 '' we achieved a complete recovery of the occluded arteries caliber (mTICI 3) and a good performance status of our patients on discharge, with the only remarkable complication of a mild asymptomatic subarachnoid bleeding in one of them. The 90-days mRS in those patients was less or equal than 2, and they have not experienced recurrence of the strokes in the long term follow-up. Conclusions: In our experience, the Elutax "3 '' might be a safe and effective therapeutic option in acute large vessel occlusion secondary to intracranial atherosclerotic disease. However, further studies will be necessary to evaluate the efficacy and safety of this device.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://isabial.portalinvestigacion.com/publicaciones6500
url https://isabial.portalinvestigacion.com/publicaciones6500
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv ELSEVIER
publisher.none.fl_str_mv ELSEVIER
dc.source.none.fl_str_mv Interdisciplinary Neurosurgery-Advanced Techniques and Case Management
ISSN: 22147519
reponame:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
instname_str Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
reponame_str r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
collection r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
repository.name.fl_str_mv
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score 15.812429

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