Reproducible diagnosis of chronic lymphocytic leukemia by flow cytometry

The diagnostic criteria for CLL rely on morphology and immunophenotype. Current approaches have limitations affecting reproducibility and there is no consensus on the role of new markers. The aim of this project was to identify reproducible criteria and consensus on markers recommended for the diagn...

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Detalhes bibliográficos
Autores: Rawstron, Andy C.|||0000-0003-0798-9790, Kreuzer, Karl-Anton, Soosapilla, Asha, Spacek, Martin, Stehlikova, Olga, Gambell, Peter, McIver-Brown, Neil, Villamor, Neus|||0000-0001-6538-4111, Psarra, Katherina, Arroz, Maria, Milani, Raffaella, De La Serna, Javier|||0000-0003-3904-1101, Cedena, M.Teresa, Jakšić, Ozren|||0000-0003-4026-285X, Nomdedeu Guinot, Jose Francisco|||0000-0003-3399-346X, Moreno, Carol|||0000-0003-3275-0271, Rigolin, Gian Matteo|||0000-0002-8370-5190, Cuneo, Antonio, Johansen, Preben, Johnsen, Hans E., Rosenquist, Richard|||0000-0002-0211-8788, Niemann, Carsten Utoft, Kern, Wolfgang|||0000-0002-6452-2874, Westerman, David, Trneny, Marek|||0000-0002-6952-6073, Mulligan, Stephen, Doubek, Michael|||0000-0002-1269-6282, Pospisilova, Sarka|||0000-0001-7136-2680, Hillmen, Peter|||0000-0001-5617-4403, Oscier, David, Hallek, Michael, Ghia, Paolo|||0000-0003-3750-7342, Montserrat, Emili
Formato: artículo
Fecha de publicación:2018
País:España
Recursos:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:287535
Acesso em linha:https://ddd.uab.cat/record/287535
https://dx.doi.org/urn:doi:10.1002/cyto.b.21595
Access Level:acceso abierto
Palavra-chave:Chronic lymphocytic leukemia
Flow cytometry
Diagnosis
Descrição
Resumo:The diagnostic criteria for CLL rely on morphology and immunophenotype. Current approaches have limitations affecting reproducibility and there is no consensus on the role of new markers. The aim of this project was to identify reproducible criteria and consensus on markers recommended for the diagnosis of CLL. ERIC/ESCCA members classified 14 of 35 potential markers as "required" or "recommended" for CLL diagnosis, consensus being defined as.