Relationship between genome and epigenome - challenges and requirements for future research

Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges,...

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Detalhes bibliográficos
Autores: Almouzni, Geneviève, Estivill, Xavier, 1955-, Ossowski, Stephan, Widschwendter, Martin
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Recursos:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/23245
Acesso em linha:http://hdl.handle.net/10230/23245
http://dx.doi.org/10.1186/1471-2164-15-487
Access Level:acceso abierto
Palavra-chave:Epigènesi
Genòmica
Genome
Epigenome
Microbiome
Environment
Descrição
Resumo:Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges, we have come up with nine major conclusions to set the vision for future policies and research agendas at the European level.