Treatment Algorithms for Inflammatory Myopathies in Adults
Purpose of Review Inflammatory myopathies are a heterogeneous group of systemic autoimmune disorders with highly variable clinical presentations. The limited number of clinical trials has hindered the development of strong evidence-based management strategies. Therefore, there is a pressing need for...
| Autores: | , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:325985 |
| Acceso en línea: | https://ddd.uab.cat/record/325985 https://dx.doi.org/urn:doi:10.1007/s40674-025-00239-5 |
| Access Level: | acceso abierto |
| Palabra clave: | Inflammatory myopathy Myositis Dermatomyositis Antisynthetase syndrome Immune-mediated necrotizing myopathy Myositis guidelines Myositis treating algorithm Myositis clinical practice |
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Treatment Algorithms for Inflammatory Myopathies in Adultsfrom Guidelines to Clinical PracticeSelva O'Callaghan, Albert|||0000-0003-2823-9761Trallero Araguás, Ernesto|||0000-0003-3365-4521Gil Vila, Albert|||0000-0003-2786-2009Matas-Garcia, Ana|||0000-0002-9184-8079Edo-Fernandez, ClaraMilisenda, José César|||0000-0003-0151-7872Pinal Fernandez, Iago|||0000-0001-6338-9218Inflammatory myopathyMyositisDermatomyositisAntisynthetase syndromeImmune-mediated necrotizing myopathyMyositis guidelinesMyositis treating algorithmMyositis clinical practicePurpose of Review Inflammatory myopathies are a heterogeneous group of systemic autoimmune disorders with highly variable clinical presentations. The limited number of clinical trials has hindered the development of strong evidence-based management strategies. Therefore, there is a pressing need for consensus-driven treatment guidelines tailored to the various clinical and immunological phenotypes. This review combines existing published guidelines with the authors' clinical experience to provide a comprehensive, pragmatic approach to management. Recent Findings A comparative review of existing treatment guidelines was recently published, revealing significant heterogeneity in therapeutic approaches and recommendations. This observation is consistent with our own experience during a multidisciplinary meeting, primarily involving internal medicine specialists and rheumatologists. Furthermore, recent clinical trials and observational studies investigating novel therapies offer promising prospects that could influence future clinical decision-making. Summary Although establishing a unified therapeutic algorithm remains challenging, this review aims to translate current knowledge into clinical practice by integrating existing guidelines, our own clinical experience, and the most recent evidence published on the topic. 22025-01-0120252025-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/325985https://dx.doi.org/urn:doi:10.1007/s40674-025-00239-5reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengInstituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI22/00708open accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3259852026-06-06T12:50:31Z |
| dc.title.none.fl_str_mv |
Treatment Algorithms for Inflammatory Myopathies in Adults from Guidelines to Clinical Practice |
| title |
Treatment Algorithms for Inflammatory Myopathies in Adults |
| spellingShingle |
Treatment Algorithms for Inflammatory Myopathies in Adults Selva O'Callaghan, Albert|||0000-0003-2823-9761 Inflammatory myopathy Myositis Dermatomyositis Antisynthetase syndrome Immune-mediated necrotizing myopathy Myositis guidelines Myositis treating algorithm Myositis clinical practice |
| title_short |
Treatment Algorithms for Inflammatory Myopathies in Adults |
| title_full |
Treatment Algorithms for Inflammatory Myopathies in Adults |
| title_fullStr |
Treatment Algorithms for Inflammatory Myopathies in Adults |
| title_full_unstemmed |
Treatment Algorithms for Inflammatory Myopathies in Adults |
| title_sort |
Treatment Algorithms for Inflammatory Myopathies in Adults |
| dc.creator.none.fl_str_mv |
Selva O'Callaghan, Albert|||0000-0003-2823-9761 Trallero Araguás, Ernesto|||0000-0003-3365-4521 Gil Vila, Albert|||0000-0003-2786-2009 Matas-Garcia, Ana|||0000-0002-9184-8079 Edo-Fernandez, Clara Milisenda, José César|||0000-0003-0151-7872 Pinal Fernandez, Iago|||0000-0001-6338-9218 |
| author |
Selva O'Callaghan, Albert|||0000-0003-2823-9761 |
| author_facet |
Selva O'Callaghan, Albert|||0000-0003-2823-9761 Trallero Araguás, Ernesto|||0000-0003-3365-4521 Gil Vila, Albert|||0000-0003-2786-2009 Matas-Garcia, Ana|||0000-0002-9184-8079 Edo-Fernandez, Clara Milisenda, José César|||0000-0003-0151-7872 Pinal Fernandez, Iago|||0000-0001-6338-9218 |
| author_role |
author |
| author2 |
Trallero Araguás, Ernesto|||0000-0003-3365-4521 Gil Vila, Albert|||0000-0003-2786-2009 Matas-Garcia, Ana|||0000-0002-9184-8079 Edo-Fernandez, Clara Milisenda, José César|||0000-0003-0151-7872 Pinal Fernandez, Iago|||0000-0001-6338-9218 |
| author2_role |
author author author author author author |
| dc.subject.none.fl_str_mv |
Inflammatory myopathy Myositis Dermatomyositis Antisynthetase syndrome Immune-mediated necrotizing myopathy Myositis guidelines Myositis treating algorithm Myositis clinical practice |
| topic |
Inflammatory myopathy Myositis Dermatomyositis Antisynthetase syndrome Immune-mediated necrotizing myopathy Myositis guidelines Myositis treating algorithm Myositis clinical practice |
| description |
Purpose of Review Inflammatory myopathies are a heterogeneous group of systemic autoimmune disorders with highly variable clinical presentations. The limited number of clinical trials has hindered the development of strong evidence-based management strategies. Therefore, there is a pressing need for consensus-driven treatment guidelines tailored to the various clinical and immunological phenotypes. This review combines existing published guidelines with the authors' clinical experience to provide a comprehensive, pragmatic approach to management. Recent Findings A comparative review of existing treatment guidelines was recently published, revealing significant heterogeneity in therapeutic approaches and recommendations. This observation is consistent with our own experience during a multidisciplinary meeting, primarily involving internal medicine specialists and rheumatologists. Furthermore, recent clinical trials and observational studies investigating novel therapies offer promising prospects that could influence future clinical decision-making. Summary Although establishing a unified therapeutic algorithm remains challenging, this review aims to translate current knowledge into clinical practice by integrating existing guidelines, our own clinical experience, and the most recent evidence published on the topic. |
| publishDate |
2025 |
| dc.date.none.fl_str_mv |
2 2025-01-01 2025 2025-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
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article |
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https://ddd.uab.cat/record/325985 https://dx.doi.org/urn:doi:10.1007/s40674-025-00239-5 |
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https://ddd.uab.cat/record/325985 https://dx.doi.org/urn:doi:10.1007/s40674-025-00239-5 |
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Inglés eng |
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Inglés |
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eng |
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Instituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI22/00708 |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
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reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
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Universitat Autònoma de Barcelona |
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Dipòsit Digital de Documents de la UAB |
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