Piperazine-derived small molecules as potential Flaviviridae NS3 protease inhibitors. In vitro antiviral activity evaluation against Zika and Dengue viruses

© 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Detalhes bibliográficos
Autores: García-Lozano, María del Rosario, Dragoni, Filippo, Gallego, Paloma, Mazzotta, Sarah, López-Gómez, Alejandro, Boccuto, Adele, Martínez-Cortés, Carlos, Rodríguez-Martínez, Alejandro, Pérez-Sánchez, Horacio, Vega-Pérez, José Manuel, Campo, José A. del, Vicenti, Ilaria, Vega-Holm, Margarita, Iglesias-Guerra, Fernando
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/352277
Acesso em linha:http://hdl.handle.net/10261/352277
Access Level:acceso abierto
Palavra-chave:Flavivirus
NS3 protease
Small molecules inhibitors
Privileged structures
Acyl and urea piperazine derivatives
Live virus phenotypic assay
Molecular docking
Molecular modeling
Descrição
Resumo:© 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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