Noninvasive diagnosis of vulnerable coronary plaque

Myocardial infarction and sudden cardiac death are frequently the first manifestation of coronary artery disease. For this reason, screening of asymptomatic coronary atherosclerosis has become an attractive field of research in cardiovascular medicine. Necropsy studies have described histopathologic...

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Detalles Bibliográficos
Autores: Pozo, Eduardo, Agudo-Quilez, Pilar, Rojas-Gonzalez, Antonio, Alvarado, Teresa, Olivera, Maria Jose, Jimenez-Borreguero, Luis J., Alfonso, Fernando
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/5202
Acceso en línea:http://hdl.handle.net/20.500.12105/5202
Access Level:acceso abierto
Palabra clave:Atherosclerosis
Vulnerable coronary plaque
Diagnosis
Cardiac computed tomography
Cardiac magnetic resonance
COMPUTED TOMOGRAPHIC ANGIOGRAPHY
CARDIOVASCULAR-MAGNETIC-RESONANCE
ACUTE MYOCARDIAL-INFARCTION
NAVIGATED IMAGE-RECONSTRUCTION
OPTICAL COHERENCE TOMOGRAPHY
NAPKIN-RING SIGN
INTRAVASCULAR ULTRASOUND
CT ANGIOGRAPHY
CONTRAST AGENT
ATHEROSCLEROTIC PLAQUES
Descripción
Sumario:Myocardial infarction and sudden cardiac death are frequently the first manifestation of coronary artery disease. For this reason, screening of asymptomatic coronary atherosclerosis has become an attractive field of research in cardiovascular medicine. Necropsy studies have described histopathological changes associated with the development of acute coronary events. In this regard, thin-cap fibroatheroma has been identified as the main vulnerable coronary plaque feature. Hence, many imaging techniques, such as coronary computed tomography, cardiac magnetic resonance or positron emission tomography, have tried to detect noninvasively these histomorphological characteristics with different approaches. In this article, we review the role of these diagnostic tools in the detection of vulnerable coronary plaque with particular interest in their advantages and limitations as well as the clinical implications of the derived findings.