Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain

OBJECTIVE: To assess the relationship between short-term exposure to outdoor ambient air pollutants (fine particulate matter [PM2.5] and black carbon [BC]), ischemic stroke (IS) and its different subtypes, and the potential modifying effect of neighborhood greenspace and noise. METHODS: This time-st...

Descripción completa

Detalles Bibliográficos
Autores: Vivanco Hidalgo, Rosa María, Wellenius, Gregory A., Basagaña Flores, Xavier, Cirach, Marta, González, Alejandra Gómez, Ceballos, Pablo de, Zabalza, Ana, Jiménez Conde, Jordi, Soriano Tarraga, Carolina, Giralt-Steinhauer, Eva, Alastuey, Andrés, Querol, Xavier, Sunyer Deu, Jordi, Roquer, Jaume
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/34346
Acceso en línea:http://hdl.handle.net/10230/34346
http://dx.doi.org/10.1016/j.envres.2017.12.024
Access Level:acceso abierto
Palabra clave:Air pollution
Atherosclerosis
Black carbon
Ischemic stroke
id ES_9761b3e44d01e8c58ccd863b321eb2e2
oai_identifier_str oai:repositori.upf.edu:10230/34346
network_acronym_str ES
network_name_str España
repository_id_str
spelling Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, SpainVivanco Hidalgo, Rosa MaríaWellenius, Gregory A.Basagaña Flores, XavierCirach, MartaGonzález, Alejandra GómezCeballos, Pablo deZabalza, AnaJiménez Conde, JordiSoriano Tarraga, CarolinaGiralt-Steinhauer, EvaAlastuey, AndrésQuerol, XavierSunyer Deu, JordiRoquer, JaumeAir pollutionAtherosclerosisBlack carbonIschemic strokeOBJECTIVE: To assess the relationship between short-term exposure to outdoor ambient air pollutants (fine particulate matter [PM2.5] and black carbon [BC]), ischemic stroke (IS) and its different subtypes, and the potential modifying effect of neighborhood greenspace and noise. METHODS: This time-stratified case-crossover study was based on IS and transient ischemic attacks (TIA) recorded in a hospital-based prospective stroke register (BASICMAR 2005-2014) in Barcelona (Catalonia, Spain). Daily and hourly pollutant concentrations and meteorological data were obtained from monitoring stations in the city. Time-lags (from previous 72h to acute stroke onset) were analyzed. Greenness and noise were determined from the Normalized Difference Vegetation Index (NDVI) and daily average noise level at the street nearest to residential address, respectively. RESULTS: The 2742 cases with known onset date and time, living in the study area, were analyzed. After adjusting for temperature, no statistically significant association between pollutants exposure and overall stroke risk was found. In subtype analysis, an association was detected between BC exposure at 24-47h (odds ratio, 1.251; 95% confidence interval [CI], 1.001-1.552; P = 0.042) and 48-72h (1.211; 95% CI, 0.988-1.484; P = 0.065) time-lag prior to stroke onset and large-artery atherosclerosis subtype. No clear modifying effect of greenness or noise was observed. CONCLUSIONS: Overall, no association was found between PM2.5 and BC exposure and acute IS risk. By stroke subtype, large-artery atherosclerotic stroke could be triggered by daily increases in BC, a diesel fuel-related pollutant in the study area.Elsevier201820182018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/34346http://dx.doi.org/10.1016/j.envres.2017.12.024reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésEnvironmental Research. 2018 Apr;162:160-5© 2018 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/343462026-06-12T07:21:37Z
dc.title.none.fl_str_mv Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain
title Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain
spellingShingle Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain
Vivanco Hidalgo, Rosa María
Air pollution
Atherosclerosis
Black carbon
Ischemic stroke
title_short Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain
title_full Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain
title_fullStr Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain
title_full_unstemmed Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain
title_sort Short-term exposure to traffic-related air pollution and ischemic stroke onset in Barcelona, Spain
dc.creator.none.fl_str_mv Vivanco Hidalgo, Rosa María
Wellenius, Gregory A.
Basagaña Flores, Xavier
Cirach, Marta
González, Alejandra Gómez
Ceballos, Pablo de
Zabalza, Ana
Jiménez Conde, Jordi
Soriano Tarraga, Carolina
Giralt-Steinhauer, Eva
Alastuey, Andrés
Querol, Xavier
Sunyer Deu, Jordi
Roquer, Jaume
author Vivanco Hidalgo, Rosa María
author_facet Vivanco Hidalgo, Rosa María
Wellenius, Gregory A.
Basagaña Flores, Xavier
Cirach, Marta
González, Alejandra Gómez
Ceballos, Pablo de
Zabalza, Ana
Jiménez Conde, Jordi
Soriano Tarraga, Carolina
Giralt-Steinhauer, Eva
Alastuey, Andrés
Querol, Xavier
Sunyer Deu, Jordi
Roquer, Jaume
author_role author
author2 Wellenius, Gregory A.
Basagaña Flores, Xavier
Cirach, Marta
González, Alejandra Gómez
Ceballos, Pablo de
Zabalza, Ana
Jiménez Conde, Jordi
Soriano Tarraga, Carolina
Giralt-Steinhauer, Eva
Alastuey, Andrés
Querol, Xavier
Sunyer Deu, Jordi
Roquer, Jaume
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Air pollution
Atherosclerosis
Black carbon
Ischemic stroke
topic Air pollution
Atherosclerosis
Black carbon
Ischemic stroke
description OBJECTIVE: To assess the relationship between short-term exposure to outdoor ambient air pollutants (fine particulate matter [PM2.5] and black carbon [BC]), ischemic stroke (IS) and its different subtypes, and the potential modifying effect of neighborhood greenspace and noise. METHODS: This time-stratified case-crossover study was based on IS and transient ischemic attacks (TIA) recorded in a hospital-based prospective stroke register (BASICMAR 2005-2014) in Barcelona (Catalonia, Spain). Daily and hourly pollutant concentrations and meteorological data were obtained from monitoring stations in the city. Time-lags (from previous 72h to acute stroke onset) were analyzed. Greenness and noise were determined from the Normalized Difference Vegetation Index (NDVI) and daily average noise level at the street nearest to residential address, respectively. RESULTS: The 2742 cases with known onset date and time, living in the study area, were analyzed. After adjusting for temperature, no statistically significant association between pollutants exposure and overall stroke risk was found. In subtype analysis, an association was detected between BC exposure at 24-47h (odds ratio, 1.251; 95% confidence interval [CI], 1.001-1.552; P = 0.042) and 48-72h (1.211; 95% CI, 0.988-1.484; P = 0.065) time-lag prior to stroke onset and large-artery atherosclerosis subtype. No clear modifying effect of greenness or noise was observed. CONCLUSIONS: Overall, no association was found between PM2.5 and BC exposure and acute IS risk. By stroke subtype, large-artery atherosclerotic stroke could be triggered by daily increases in BC, a diesel fuel-related pollutant in the study area.
publishDate 2018
dc.date.none.fl_str_mv 2018
2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/34346
http://dx.doi.org/10.1016/j.envres.2017.12.024
url http://hdl.handle.net/10230/34346
http://dx.doi.org/10.1016/j.envres.2017.12.024
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Environmental Research. 2018 Apr;162:160-5
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869414059055513600
score 15,811543

Similares en LA Referencia