High sequence variability of myticin transcripts in hemocytes of immune-stimulated mussels suggests ancient host-pathogen interactions
Small cationic antimicrobial peptides (AMPS) are host defense molecules detected in virtually all gropus of organisms. To investigate the immuine response mechanisms of Mytilus galloprovincialis, primary and suppresion subtractive hybridization libraries were prepared from hemolymph of mussels injec...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2008 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/3013 |
| Acceso en línea: | http://hdl.handle.net/10261/3013 |
| Access Level: | acceso abierto |
| Palabra clave: | Mytilus Myticin Mussel Antimicrobial |
| Sumario: | Small cationic antimicrobial peptides (AMPS) are host defense molecules detected in virtually all gropus of organisms. To investigate the immuine response mechanisms of Mytilus galloprovincialis, primary and suppresion subtractive hybridization libraries were prepared from hemolymph of mussels injected with heat-inactivated bacteria or ply l:C, the latter mimicking viral infection. After DNA sequencing, sequence processing and similarity searching, a remarkable abundance of AMP mRNAS were identified. |
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