Development of clobetasol-loaded biodegradable nanoparticles as an endodontic intracanal medicament

The aim of current study is the development and optimization of biodegradable polymeric nanoparticles (NPs) to be used in the field of Endodontics as intracanal medication in cases of avulsed teeth with extended extra-oral time, utilizing PLGA polymers loaded with the anti-inflammatory drug clobetas...

Descripción completa

Detalles Bibliográficos
Autores: Elmsmari, Firas, González Sánchez, José Antonio, Delgado, Luis M., Espina, Marta, Duran-Sindreu, Fernando, García, Maria Luisa, Sánchez-López, Elena
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/356699
Acceso en línea:http://hdl.handle.net/10261/356699
https://api.elsevier.com/content/abstract/scopus_id/85192107782
Access Level:acceso abierto
Palabra clave:Tooth avulsion
PLGA
Clobetasol
Dental trauma
Nanoparticles
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
Descripción
Sumario:The aim of current study is the development and optimization of biodegradable polymeric nanoparticles (NPs) to be used in the field of Endodontics as intracanal medication in cases of avulsed teeth with extended extra-oral time, utilizing PLGA polymers loaded with the anti-inflammatory drug clobetasol propionate (CP).