Microencapsulated linseed oil supplementation modifies lipid profile and improves luteal function in dairy sheep

Polyunsaturated fatty acids omega 3 (PUFA- ω3) have been shown to modulate reproductive events such as ovarian follicularand luteal development, steroid and prostaglandin synthesis, and oocyte/embryo quality in different species. These effects couldbe exploited to support pregnancy and avoid early e...

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Detalles Bibliográficos
Autores: Contreras Solís, Ignacio, Porcu, Cristian, Sotgiu, Francesca Daniela, Pasciu, Valeria, Todorova, Neda, Mara, Laura, Chessa, Fabrizio, Addis, Margherita, Fiori, Myriam, Molle, Giovanni, Dattena, Maria, González-Bulnes, Antonio, Abecia, José Alfonso, Berlinguer, Fiammetta
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Universidad Pública de Navarra
Repositorio:Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
OAI Identifier:oai:academica-e.unavarra.es:2454/56471
Acceso en línea:https://hdl.handle.net/2454/56471
Access Level:acceso abierto
Palabra clave:Ewes
Fertility
Linseed oil
Lipid-metabolism status
Ovarian function
Descripción
Sumario:Polyunsaturated fatty acids omega 3 (PUFA- ω3) have been shown to modulate reproductive events such as ovarian follicularand luteal development, steroid and prostaglandin synthesis, and oocyte/embryo quality in different species. These effects couldbe exploited to support pregnancy and avoid early embryo losses that could occur in dairy sheep breeding. This study aimed toevaluate the effectiveness of dietary supplementation of microencapsulated/by-passed linseed oil (LO) on ovarian function, em-bryo implantation rates, and lipid profiles of Sarda ewes during their early pregnancy. Our results demonstrated that the intakeof microencapsulated LO at a level of 4.0% of fresh matter increased the plasmatic concentrations of PUFASω3 (p < 0.01) andprogesterone (p < 0.05), as well as cholesterol (p < 0.01), triglyceride (p < 0.001), high-density lipoprotein (p < 0.001), and non-esterified fatty acids (p < 0.05). The percentage of ewes in estrus, ovulation rate per mated ewe, number of embryos per ewe, andpregnancy rates were similar between treated and control groups. In conclusion, dietary supplementation of by-pass LO duringthe preimplantation period increased PUFAS- ω3 distribution at systemic and local levels. Also, this supplementation modifiedthe ewe's lipid profile and improved luteal function with a possible positive effect on embryo-maternal crosstalk and embryoimplantation rate during and after the maternal recognition of pregnancy.