Use of Natural Polymers for the Encapsulation of Eugenol by Spray Drying

<strong>Background:</strong> Eugenol is a colourless or yellowish compound whose presence in clove essential oil surpasses the 75% of its composition. This phenylpropanoid, widely used as an antiseptic, anaesthetic and antioxidant, can be extracted by steam distillation from the dried fl...

Descripción completa

Detalles Bibliográficos
Autores: Nardi Ricart, Anna, Caballero Roman, Aitor, Vila, Roser, Cañigueral i Folcarà, Salvador, Ticó Grau, Josep R., Miñarro Carmona, Montserrat
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/216114
Acceso en línea:https://hdl.handle.net/2445/216114
Access Level:acceso abierto
Palabra clave:Polímers
Nanopartícules
Polymers
Nanoparticles
Descripción
Sumario:<strong>Background:</strong> Eugenol is a colourless or yellowish compound whose presence in clove essential oil surpasses the 75% of its composition. This phenylpropanoid, widely used as an antiseptic, anaesthetic and antioxidant, can be extracted by steam distillation from the dried flower buds of <em>Syzygium aromaticum</em> (L.). Due to its chemical instability in presence of light and air, it should be protected when developing a formulation to avoid or minimise its degradation. <strong>Methods: </strong>A promising approach would be encapsulation by spray drying, using natural coating products such as maltodextrin, gum arabic, and soy lecithin. To do so, a factorial design was carried out to evaluate the effect of five variables at two levels (inlet temperature, aspirator and flow rate, method of homogenisation of the emulsion and its eugenol:polymers ratio). Studied outcomes were yield and outlet temperature of the spray drying process, eugenol encapsulation efficiency, and particle size expressed as d<sub>(0.9)</sub>. <strong>Results:</strong> The best three formulations were prepared by using a lower amount of eugenol than polymers (1:2 ratio), homogenised by Ultra-Turrax<sup>®</sup>, and pumped to the spray dryer at 35 m<sup>3</sup>/h. Inlet temperature and flow rate varied in the top three formulations, but their values in the best formulation (DF22) were 130°C and 4.5 mL/min. These microcapsules encapsulated between 47.37% and 65.69% of eugenol and were spray-dried achieving more than a 57.20% of product recovery. Their size, ranged from 22.40 μm to 55.60 μm. <strong>Conclusions:</strong> Overall, the whole spray drying process was optimised, and biodegradable stable polymeric microcapsules containing eugenol were successfully prepared.