Efficacy of different 8 h time-restricted eating schedules on visceral adipose tissue and cardiometabolic health: A study protocol

Background and aims To investigate the efficacy and feasibility of three different 8 h time-restricted eating (TRE) schedules (i.e., early, late, and self-selected) compared to each other and to a usual-care (UC) intervention on visceral adipose tissue (VAT) and cardiometabolic health in men and wom...

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Detalles Bibliográficos
Autores: Dote-Montero, Manuel, Merchan-Ramirez, Elisa, Oses, Maddi, Echarte, Jon, Clavero-Jimeno, Antonio, Alcantara, JMA, Camacho-Cardenosa, Alba, Cupeiro, Rocío, Rodríguez-Miranda, María de las Nieves, López-Vázquez, Alejandro, Amaro-Gahete, Francisco J., González Cejudo, María Trinidad, Martin-Olmedo, Juan J., Molina-Fernandez, Marcos, García Pérez, Patricia Virginia, Contreras-Bolívar, Victoria, Muñoz-Garach, Araceli, Andreo-López, María C., Carneiro-Barrera, Almudena, Miranda-Ferrúa, Emiliano, Zugasti, Ana, Petrina, Estrella, Álvarez de Eulate, Natalia, Goñi, Elena, Ribelles, María Jesús, Armendáriz Brugos, Cristina, Izquierdo, Claudia, Fernández-Puggioni, Victoria, Galbete, Arkaitz, Villanueva, Arantxa, Medrano, María, Alfaro-Magallanes, Víctor Manuel, Muñoz-Torres, Manuel, Martín-Rodríguez, José L., Idoate, Fernando, Cabeza, Rafael, Ruiz, Jonatan R., Labayen, Idoia
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universidad Loyola Andalucía
Repositorio:Brújula
OAI Identifier:oai:repositorio.uloyola.es:20.500.12412/5736
Acceso en línea:https://hdl.handle.net/20.500.12412/5736
Access Level:acceso abierto
Palabra clave:Intermittent fasting
Chrononutrition
Circadian rhythms
Time-restricted feeding
Fat mass
Insulin resistance
Descripción
Sumario:Background and aims To investigate the efficacy and feasibility of three different 8 h time-restricted eating (TRE) schedules (i.e., early, late, and self-selected) compared to each other and to a usual-care (UC) intervention on visceral adipose tissue (VAT) and cardiometabolic health in men and women. Methods and results Anticipated 208 adults (50% women) aged 30–60 years, with overweight/obesity (25 ≤ BMI<40 kg/m2) and with mild metabolic impairments will be recruited for this parallel-group, multicenter randomized controlled trial. Participants will be randomly allocated (1:1:1:1) to one of four groups for 12 weeks: UC, early TRE, late TRE or self-selected TRE. The UC group will maintain their habitual eating window and receive, as well as the TRE groups, healthy lifestyle education for weight management. The early TRE group will start eating not later than 10:00, and the late TRE group not before 13:00. The self-selected TRE group will select an 8 h eating window before the intervention and maintain it over the intervention. The primary outcome is changes in VAT, whereas secondary outcomes include body composition and cardiometabolic risk factors. Conclusion This study will determine whether the timing of the eating window during TRE impacts its efficacy on VAT, body composition and cardiometabolic risk factors and provide insights about its feasibility.

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