Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)

Experimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population-based case-control study (MCC-Spain) if the time-of-day when physical activity is don...

Descripción completa

Detalles Bibliográficos
Autores: Weitzer, Jakob, Castaño Vinyals, Gemma, Aragonés, Nuria, Alguacil Ojeda, Juan
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad de Huelva (UHU)
Repositorio:Arias Montano. Repositorio Institucional de la Universidad de Huelva
Idioma:inglés
OAI Identifier:oai:ariasmontano.uhu.es:10272/18996
Acceso en línea:http://hdl.handle.net/10272/18996
Access Level:acceso abierto
Palabra clave:Breast
Cancer
Circadian disruption
Physical activity
Prostate
id ES_93c93a8b17f0042b1ecdfdcf7fc74a8a
oai_identifier_str oai:ariasmontano.uhu.es:10272/18996
network_acronym_str ES
network_name_str España
repository_id_str
spelling Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)Weitzer, JakobCastaño Vinyals, GemmaAragonés, NuriaAlguacil Ojeda, JuanBreastCancerCircadian disruptionPhysical activityProstateExperimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population-based case-control study (MCC-Spain) if the time-of-day when physical activity is done affects prostate and breast cancer risk. Lifetime recreational and household physical activity was assessed by in-person interviews. Information on time-of-day of activity (assessed approximately 3 years after the assessment of lifetime physical activity and confounders) was available for 781 breast cancer cases, 865 population female controls, 504 prostate cases and 645 population male controls from 10 Spanish regions, 2008-2013. We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) for different activity timings compared to inactive subjects using unconditional logistic regression adjusting for confounders. Early morning (8-10 AM) activity was associated with a protective effect compared to no physical activity for both breast (OR = 0.74, 95% CI = 0.48-1.15) and prostate cancer (OR = 0.73, 95% CI = 0.44-1.20); meta-OR for the two cancers combined 0.74 (95%CI = 0.53-1.02). There was no effect observed for breast or prostate cancer for late morning to afternoon activity while a protective effect was also observed for evening activity only for prostate cancer (OR = 0.75, 95% CI = 0.45-1.24). Protective effects of early morning activity were more pronounced for intermediate/ evening chronotypes for both cancers. This is the first population-based investigation identifying a differential effect of timing of physical activity on cancer risk with more pronounced effects for morning hour activity. Our results, if confirmed, may improve current physical activity recommendations for cancer prevention.Wiley20202020-10-0120202020-10-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10272/18996reponame:Arias Montano. Repositorio Institucional de la Universidad de Huelvainstname:Universidad de Huelva (UHU)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccessoai:ariasmontano.uhu.es:10272/189962026-06-02T14:58:11Z
dc.title.none.fl_str_mv Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
spellingShingle Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
Weitzer, Jakob
Breast
Cancer
Circadian disruption
Physical activity
Prostate
title_short Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title_full Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title_fullStr Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title_full_unstemmed Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
title_sort Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)
dc.creator.none.fl_str_mv Weitzer, Jakob
Castaño Vinyals, Gemma
Aragonés, Nuria
Alguacil Ojeda, Juan
author Weitzer, Jakob
author_facet Weitzer, Jakob
Castaño Vinyals, Gemma
Aragonés, Nuria
Alguacil Ojeda, Juan
author_role author
author2 Castaño Vinyals, Gemma
Aragonés, Nuria
Alguacil Ojeda, Juan
author2_role author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Breast
Cancer
Circadian disruption
Physical activity
Prostate
topic Breast
Cancer
Circadian disruption
Physical activity
Prostate
description Experimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population-based case-control study (MCC-Spain) if the time-of-day when physical activity is done affects prostate and breast cancer risk. Lifetime recreational and household physical activity was assessed by in-person interviews. Information on time-of-day of activity (assessed approximately 3 years after the assessment of lifetime physical activity and confounders) was available for 781 breast cancer cases, 865 population female controls, 504 prostate cases and 645 population male controls from 10 Spanish regions, 2008-2013. We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) for different activity timings compared to inactive subjects using unconditional logistic regression adjusting for confounders. Early morning (8-10 AM) activity was associated with a protective effect compared to no physical activity for both breast (OR = 0.74, 95% CI = 0.48-1.15) and prostate cancer (OR = 0.73, 95% CI = 0.44-1.20); meta-OR for the two cancers combined 0.74 (95%CI = 0.53-1.02). There was no effect observed for breast or prostate cancer for late morning to afternoon activity while a protective effect was also observed for evening activity only for prostate cancer (OR = 0.75, 95% CI = 0.45-1.24). Protective effects of early morning activity were more pronounced for intermediate/ evening chronotypes for both cancers. This is the first population-based investigation identifying a differential effect of timing of physical activity on cancer risk with more pronounced effects for morning hour activity. Our results, if confirmed, may improve current physical activity recommendations for cancer prevention.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-10-01
2020
2020-10-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10272/18996
url http://hdl.handle.net/10272/18996
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución-NoComercial-SinDerivadas 3.0 España
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución-NoComercial-SinDerivadas 3.0 España
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Arias Montano. Repositorio Institucional de la Universidad de Huelva
instname:Universidad de Huelva (UHU)
instname_str Universidad de Huelva (UHU)
reponame_str Arias Montano. Repositorio Institucional de la Universidad de Huelva
collection Arias Montano. Repositorio Institucional de la Universidad de Huelva
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869413626399424512
score 15,811543

Similares en LA Referencia