Ultrasound-activated nanomaterials for therapeutics

Ultrasound has attracted much attention in recent years as an external stimulus capable of activating different types of nanomaterials for therapeutic application. One of the characteristics that makes ultrasound an especially appealing triggering stimulus for nanomedicine is its capacity to be non-...

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Detalles Bibliográficos
Autores: Paris, J.L., Vallet Regí, María Dulce Nombre
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/5993
Acceso en línea:https://hdl.handle.net/20.500.14352/5993
Access Level:acceso abierto
Palabra clave:546
615.46
Ultrasound
Nanomedicine
Stimuli-responsive
Materiales
Química inorgánica (Farmacia)
3312 Tecnología de Materiales
Descripción
Sumario:Ultrasound has attracted much attention in recent years as an external stimulus capable of activating different types of nanomaterials for therapeutic application. One of the characteristics that makes ultrasound an especially appealing triggering stimulus for nanomedicine is its capacity to be non-invasively applied in a focused manner at deep regions of the body. Combining ultrasound with nanoparticles, different biological effects can be achieved. In this work, an overview of the four main types of inducible responses will be provided: inducing drug release, producing ultrasound-derived biological effects, modifying nanoparticle biodistribution and developing theranostic agents. Several examples of each one of these applications are presented here to illustrate the key concepts underlying recent developments in the discipline.