Respiratory microbiota and lower respiratory tract disease

INTRODUCTION: The respiratory airways harbor a complex succession of ecological niches with distinct but related bacterial communities. Particular challenges of respiratory microbiome research have led to limited scientific output compared to other human microbiomes. Areas covered: In this review, w...

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Detalles Bibliográficos
Autores: Lanaspa, Miguel, Bassat Orellana, Quique, Medeiros, Marcia Melo, Muñoz-Almagro, Carmen
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2017
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/114190
Acceso en línea:https://hdl.handle.net/2445/114190
Access Level:acceso abierto
Palabra clave:Malalties de l'aparell respiratori
Bacteris
Respiratory organs diseases
Bacteria
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spelling Respiratory microbiota and lower respiratory tract diseaseLanaspa, MiguelBassat Orellana, QuiqueMedeiros, Marcia MeloMuñoz-Almagro, CarmenMalalties de l'aparell respiratoriBacterisRespiratory organs diseasesBacteriaINTRODUCTION: The respiratory airways harbor a complex succession of ecological niches with distinct but related bacterial communities. Particular challenges of respiratory microbiome research have led to limited scientific output compared to other human microbiomes. Areas covered: In this review, we summarize the current state of knowledge of the bacterial respiratory microbiome, with a particular focus on associations between the respiratory microbiome and lower respiratory tract conditions. Expert commentary: There is growing evidence that the respiratory microbiome is associated with lower respiratory infectious diseases and related conditions. Most respiratory microbiome reports are metataxonomic cross-sectional or case-control studies with relatively small sample sizes. Large, prospective projects with metatranscriptomics or metabolomics approach are needed to unravel the effect of the respiratory microbiome on health-related conditions. Moreover, standardization in sampling, library preparation, sequencing techniques and data analysis should be encouraged.Taylor & Francis2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttps://hdl.handle.net/2445/114190Articles publicats en revistes (ISGlobal)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: http://dx.doi.org/10.1080/14787210.2017.1349609Expert Review of Anti-Infective Therapy, 2017, vol. 15, num. 7, p. 703-711http://dx.doi.org/10.1080/14787210.2017.1349609(c) Taylor & Francis , 2017info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1141902026-05-27T06:46:51Z
dc.title.none.fl_str_mv Respiratory microbiota and lower respiratory tract disease
title Respiratory microbiota and lower respiratory tract disease
spellingShingle Respiratory microbiota and lower respiratory tract disease
Lanaspa, Miguel
Malalties de l'aparell respiratori
Bacteris
Respiratory organs diseases
Bacteria
title_short Respiratory microbiota and lower respiratory tract disease
title_full Respiratory microbiota and lower respiratory tract disease
title_fullStr Respiratory microbiota and lower respiratory tract disease
title_full_unstemmed Respiratory microbiota and lower respiratory tract disease
title_sort Respiratory microbiota and lower respiratory tract disease
dc.creator.none.fl_str_mv Lanaspa, Miguel
Bassat Orellana, Quique
Medeiros, Marcia Melo
Muñoz-Almagro, Carmen
author Lanaspa, Miguel
author_facet Lanaspa, Miguel
Bassat Orellana, Quique
Medeiros, Marcia Melo
Muñoz-Almagro, Carmen
author_role author
author2 Bassat Orellana, Quique
Medeiros, Marcia Melo
Muñoz-Almagro, Carmen
author2_role author
author
author
dc.subject.none.fl_str_mv Malalties de l'aparell respiratori
Bacteris
Respiratory organs diseases
Bacteria
topic Malalties de l'aparell respiratori
Bacteris
Respiratory organs diseases
Bacteria
description INTRODUCTION: The respiratory airways harbor a complex succession of ecological niches with distinct but related bacterial communities. Particular challenges of respiratory microbiome research have led to limited scientific output compared to other human microbiomes. Areas covered: In this review, we summarize the current state of knowledge of the bacterial respiratory microbiome, with a particular focus on associations between the respiratory microbiome and lower respiratory tract conditions. Expert commentary: There is growing evidence that the respiratory microbiome is associated with lower respiratory infectious diseases and related conditions. Most respiratory microbiome reports are metataxonomic cross-sectional or case-control studies with relatively small sample sizes. Large, prospective projects with metatranscriptomics or metabolomics approach are needed to unravel the effect of the respiratory microbiome on health-related conditions. Moreover, standardization in sampling, library preparation, sequencing techniques and data analysis should be encouraged.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/114190
url https://hdl.handle.net/2445/114190
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://dx.doi.org/10.1080/14787210.2017.1349609
Expert Review of Anti-Infective Therapy, 2017, vol. 15, num. 7, p. 703-711
http://dx.doi.org/10.1080/14787210.2017.1349609
dc.rights.none.fl_str_mv (c) Taylor & Francis , 2017
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Taylor & Francis , 2017
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv Articles publicats en revistes (ISGlobal)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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