Assessing the impact of COVID-19 on liver cancer management (CERO-19)
Background & aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether the schedule of LC screening or procedures has been interrupted or delay...
| Autores: | , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:10230/47958 |
| Acceso en línea: | http://hdl.handle.net/10230/47958 http://dx.doi.org/10.1016/j.jhepr.2021.100260 |
| Access Level: | acceso abierto |
| Palabra clave: | BCLC, Barcelona Clinic Liver Cancer CERO-19, Liver Cancer Outcome in the COVID-19-pandemic Project COVID-19 COVID-19, coronavirus disease 2019 Cholangiocarcinoma Clinical trials ENS-CCA, European Network for the Study of Cholangiocarcinoma HCC, hepatocellular carcinoma Hepatocellular carcinoma LC, liver cancer LT, liver transplantation Liver cancer Management Nurses SARS-CoV-2, severe acute respiratory syndrome coronavirus-2 iCCA, intrahepatic cholangiocarcinoma |
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Assessing the impact of COVID-19 on liver cancer management (CERO-19)Muñoz-Martínez, SergioColl Estrada, SusannaReig, MaríaBCLC, Barcelona Clinic Liver CancerCERO-19, Liver Cancer Outcome in the COVID-19-pandemic ProjectCOVID-19COVID-19, coronavirus disease 2019CholangiocarcinomaClinical trialsENS-CCA, European Network for the Study of CholangiocarcinomaHCC, hepatocellular carcinomaHepatocellular carcinomaLC, liver cancerLT, liver transplantationLiver cancerManagementNursesSARS-CoV-2, severe acute respiratory syndrome coronavirus-2iCCA, intrahepatic cholangiocarcinomaBackground & aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether the schedule of LC screening or procedures has been interrupted or delayed because of the COVID-19 pandemic. Methods: An international survey evaluated the impact of the COVID-19 pandemic on clinical practice and clinical trials from March 2020 to June 2020, as the first phase of a multicentre, international, and observational project. The focus was on patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma, cared for around the world during the first COVID-19 pandemic wave. Results: Ninety-one centres expressed interest to participate and 76 were included in the analysis, from Europe, South America, North America, Asia, and Africa (73.7%, 17.1%, 5.3%, 2.6%, and 1.3% per continent, respectively). Eighty-seven percent of the centres modified their clinical practice: 40.8% the diagnostic procedures, 80.9% the screening programme, 50% cancelled curative and/or palliative treatments for LC, and 41.7% modified the liver transplantation programme. Forty-five out of 69 (65.2%) centres in which clinical trials were running modified their treatments in that setting, but 58.1% were able to recruit new patients. The phone call service was modified in 51.4% of centres which had this service before the COVID-19 pandemic (n = 19/37). Conclusions: The first wave of the COVID-19 pandemic had a tremendous impact on the routine care of patients with liver cancer. Modifications in screening, diagnostic, and treatment algorithms may have significantly impaired the outcome of patients. Ongoing data collection and future analyses will report the benefits and disadvantages of the strategies implemented, aiding future decision-making. Lay summary: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems globally. Herein, we assessed the impact of the first wave pandemic on patients with liver cancer and found that routine care for these patients has been majorly disrupted, which could have a significant impact on outcomes.Elsevier202120212021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/47958http://dx.doi.org/10.1016/j.jhepr.2021.100260reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésJHEP Rep. 2021;3(3):100260© 2021 The Authors. Published by Elsevier B.V. on behalf of European Association for the Study of the Liver (EASL). This is anopen access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10230/479582026-05-29T05:05:01Z |
| dc.title.none.fl_str_mv |
Assessing the impact of COVID-19 on liver cancer management (CERO-19) |
| title |
Assessing the impact of COVID-19 on liver cancer management (CERO-19) |
| spellingShingle |
Assessing the impact of COVID-19 on liver cancer management (CERO-19) Muñoz-Martínez, Sergio BCLC, Barcelona Clinic Liver Cancer CERO-19, Liver Cancer Outcome in the COVID-19-pandemic Project COVID-19 COVID-19, coronavirus disease 2019 Cholangiocarcinoma Clinical trials ENS-CCA, European Network for the Study of Cholangiocarcinoma HCC, hepatocellular carcinoma Hepatocellular carcinoma LC, liver cancer LT, liver transplantation Liver cancer Management Nurses SARS-CoV-2, severe acute respiratory syndrome coronavirus-2 iCCA, intrahepatic cholangiocarcinoma |
| title_short |
Assessing the impact of COVID-19 on liver cancer management (CERO-19) |
| title_full |
Assessing the impact of COVID-19 on liver cancer management (CERO-19) |
| title_fullStr |
Assessing the impact of COVID-19 on liver cancer management (CERO-19) |
| title_full_unstemmed |
Assessing the impact of COVID-19 on liver cancer management (CERO-19) |
| title_sort |
Assessing the impact of COVID-19 on liver cancer management (CERO-19) |
| dc.creator.none.fl_str_mv |
Muñoz-Martínez, Sergio Coll Estrada, Susanna Reig, María |
| author |
Muñoz-Martínez, Sergio |
| author_facet |
Muñoz-Martínez, Sergio Coll Estrada, Susanna Reig, María |
| author_role |
author |
| author2 |
Coll Estrada, Susanna Reig, María |
| author2_role |
author author |
| dc.subject.none.fl_str_mv |
BCLC, Barcelona Clinic Liver Cancer CERO-19, Liver Cancer Outcome in the COVID-19-pandemic Project COVID-19 COVID-19, coronavirus disease 2019 Cholangiocarcinoma Clinical trials ENS-CCA, European Network for the Study of Cholangiocarcinoma HCC, hepatocellular carcinoma Hepatocellular carcinoma LC, liver cancer LT, liver transplantation Liver cancer Management Nurses SARS-CoV-2, severe acute respiratory syndrome coronavirus-2 iCCA, intrahepatic cholangiocarcinoma |
| topic |
BCLC, Barcelona Clinic Liver Cancer CERO-19, Liver Cancer Outcome in the COVID-19-pandemic Project COVID-19 COVID-19, coronavirus disease 2019 Cholangiocarcinoma Clinical trials ENS-CCA, European Network for the Study of Cholangiocarcinoma HCC, hepatocellular carcinoma Hepatocellular carcinoma LC, liver cancer LT, liver transplantation Liver cancer Management Nurses SARS-CoV-2, severe acute respiratory syndrome coronavirus-2 iCCA, intrahepatic cholangiocarcinoma |
| description |
Background & aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether the schedule of LC screening or procedures has been interrupted or delayed because of the COVID-19 pandemic. Methods: An international survey evaluated the impact of the COVID-19 pandemic on clinical practice and clinical trials from March 2020 to June 2020, as the first phase of a multicentre, international, and observational project. The focus was on patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma, cared for around the world during the first COVID-19 pandemic wave. Results: Ninety-one centres expressed interest to participate and 76 were included in the analysis, from Europe, South America, North America, Asia, and Africa (73.7%, 17.1%, 5.3%, 2.6%, and 1.3% per continent, respectively). Eighty-seven percent of the centres modified their clinical practice: 40.8% the diagnostic procedures, 80.9% the screening programme, 50% cancelled curative and/or palliative treatments for LC, and 41.7% modified the liver transplantation programme. Forty-five out of 69 (65.2%) centres in which clinical trials were running modified their treatments in that setting, but 58.1% were able to recruit new patients. The phone call service was modified in 51.4% of centres which had this service before the COVID-19 pandemic (n = 19/37). Conclusions: The first wave of the COVID-19 pandemic had a tremendous impact on the routine care of patients with liver cancer. Modifications in screening, diagnostic, and treatment algorithms may have significantly impaired the outcome of patients. Ongoing data collection and future analyses will report the benefits and disadvantages of the strategies implemented, aiding future decision-making. Lay summary: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems globally. Herein, we assessed the impact of the first wave pandemic on patients with liver cancer and found that routine care for these patients has been majorly disrupted, which could have a significant impact on outcomes. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021 2021 2021 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10230/47958 http://dx.doi.org/10.1016/j.jhepr.2021.100260 |
| url |
http://hdl.handle.net/10230/47958 http://dx.doi.org/10.1016/j.jhepr.2021.100260 |
| dc.language.none.fl_str_mv |
Inglés |
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Inglés |
| dc.relation.none.fl_str_mv |
JHEP Rep. 2021;3(3):100260 |
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http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
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application/pdf application/pdf |
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Elsevier |
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Elsevier |
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