Early intravenous nitroglycerin use in prehospital setting and in the emergency department to treat patients with acute heart failure

Background and objective: Although recommended for the treatment of acute heart failure (AHF), the use of intravenous (IV) nitroglycerin (NTG) is supported by scarce and contradicting evidence. In the current analysis, we have assessed the impact of IV NTG administration by EMS or in emergency depar...

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Detalles Bibliográficos
Autores: Miró, Oscar|||0000-0002-7924-9751, Llorens Soriano, Pere|||0000-0002-9291-7179, Freund, Yonathan, Davison, Beth A., Takagi, Koji, Herrero-Puente, Pablo|||0000-0002-5529-5008, Jacob, Javier|||0000-0003-1101-1066, Martín-Sánchez, Francisco Javier|||0000-0002-5970-725X, Gil, Víctor, Rossello, Xavier|||0000-0001-6783-8463, Alquézar-Arbé, A.|||0000-0003-4164-274X, Jiménez-Fábrega, Francesc X., Masip, Josep|||0000-0002-8612-9889, Mebazaa, Alexandre|||0000-0001-8715-7753, Cotter, Gad|||0000-0002-9613-3339
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:270206
Acceso en línea:https://ddd.uab.cat/record/270206
https://dx.doi.org/urn:doi:10.1016/j.ijcard.2021.09.031
Access Level:acceso abierto
Palabra clave:Acute heart failure
Nitrates
Nitroglycerine
Outcome
Mortality
Descripción
Sumario:Background and objective: Although recommended for the treatment of acute heart failure (AHF), the use of intravenous (IV) nitroglycerin (NTG) is supported by scarce and contradicting evidence. In the current analysis, we have assessed the impact of IV NTG administration by EMS or in emergency department (ED) on outcomes of AHF patients. Methods: We analyze AHF patients included by 45 hospitals that were delivered to ED by EMS. Patients were grouped according to whether treatment with IV NTG was started by EMS before ED admission (preED-NTG), during the ED stay (ED-NTG) or were untreated with IV NTG (no-NTG, control group). In-hospital, 30-day and 365-day all-cause mortality, prolonged hospitalization (.

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