Water T2 could predict functional decline in patients with dysferlinopathy

[Background]: Water T2 (T2H2O ) mapping is increasingly being used in muscular dystrophies to assess active muscle damage. It has been suggested as a surrogate outcome measure for clinical trials. Here, we investigated the prognostic utility of T2H2O to identify changes in muscle function over time...

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Detalles Bibliográficos
Autores: Moore, Ursula, Caldas de Almeida Araújo, Ericky, Reyngoudt, Harmen, Gordish-Dressman, Heather, Smith, Fiona E., Wilson, Ian, James, Meredith K., Mayhew, Anna, Rufibach, Laura, Day, John W., Jones, Kristi J., Bharucha-Goebel, Diana X., Salort-Campana, Emmanuelle, Pestronk, Alan, Walter, Maggie C., Paradas, Carmen, Stojkovic, Tanya, Mori-Yoshimura, Madoka, Bravver, Elena, Pegoraro, Elena, Mendell, Jerry R., Bushby, Kate, Blamire, Andrew M., Straub, Volker, Carlier, Pierre G., Díaz-Manera, Jordi
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/306900
Acceso en línea:http://hdl.handle.net/10261/306900
https://api.elsevier.com/content/abstract/scopus_id/85137325319
Access Level:acceso abierto
Palabra clave:Magnetic resonance imaging
Water T2
Limb girdle muscular dystrophy
Limb girdle muscular dystrophy R2
Limb girdle muscular dystrophy 2B
Descripción
Sumario:[Background]: Water T2 (T2H2O ) mapping is increasingly being used in muscular dystrophies to assess active muscle damage. It has been suggested as a surrogate outcome measure for clinical trials. Here, we investigated the prognostic utility of T2H2O to identify changes in muscle function over time in limb girdle muscular dystrophies.

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