Asymmetric epoxidation with H2O2 by manipulating the electronic properties of non-heme iron catalysts

A non-heme iron complex that catalyzes highly enantioselective epoxidation of olefins with H2O2 is described. Improvement of enantiomeric excesses is attained by the use of catalytic amounts of carboxylic acid additives. Electronic effects imposed by the ligand on the iron center are shown to synerg...

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Detalles Bibliográficos
Autores: Cussó Forest, Olaf, Garcia Bosch, Isaac, Ribas Salamaña, Xavi, Lloret Fillol, Julio, Costas Salgueiro, Miquel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10256/10022
Acceso en línea:http://hdl.handle.net/10256/10022
Access Level:acceso embargado
Palabra clave:Epòxids
Epoxy compounds
Catalitzadors
Catalysts
Compostos heterocíclics
Heterocyclic compounds
Descripción
Sumario:A non-heme iron complex that catalyzes highly enantioselective epoxidation of olefins with H2O2 is described. Improvement of enantiomeric excesses is attained by the use of catalytic amounts of carboxylic acid additives. Electronic effects imposed by the ligand on the iron center are shown to synergistically cooperate with catalytic amounts of carboxylic acids in promoting efficient O-O cleavage and creating highly chemo-and enantioselective epoxidizing species which provide a broad range of epoxides in synthetically valuable yields and short reaction times