An optimal control model to design strategies for reducing the spread of the Ebola virus disease

In this work, we formulate an epidemiological model for studying the spread of Ebola virus disease in a considered territory. This model includes the effect of various control measures, such as: vaccination, education campaigns, early detection campaigns, increase of sanitary measures in hospital, q...

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Detalles Bibliográficos
Autores: Seck, Rama, Ngom, Diène, Ivorra, Benjamín Pierre Paul, Ramos Del Olmo, Ángel Manuel
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/115238
Acceso en línea:https://hdl.handle.net/20.500.14352/115238
Access Level:acceso abierto
Palabra clave:Epidemiological modeling
Optimal control
Ebola virus disease
Deterministic models
Biomatemáticas
Investigación operativa (Matemáticas)
Enfermedades infecciosas
3202 Epidemiología
12 Matemáticas
Descripción
Sumario:In this work, we formulate an epidemiological model for studying the spread of Ebola virus disease in a considered territory. This model includes the effect of various control measures, such as: vaccination, education campaigns, early detection campaigns, increase of sanitary measures in hospital, quarantine of infected individuals and restriction of movement between geographical areas. Using optimal control theory, we determine an optimal control strategy which aims to reduce the number of infected individuals, according to some operative restrictions (e.g., economical, logistic, etc.). Furthermore, we study the existence and uniqueness of the optimal control. Finally, we illustrate the interest of the obtained results by considering numerical experiments based on real data.