Stroke prevention in patients with arterial hypertension: recommendations of the Spanish Society of Neurology's Stroke Study Group

Objective: To update the recommendations of the Spanish Society of Neurology on primary and secondary stroke prevention in patients with arterial hypertension. Development: We proposed several questions to identify practical issues for the management of blood pressure (BP) in stroke prevention, anal...

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Detalles Bibliográficos
Autores: Rodríguez-Yáñez, M., Gómez Choco, M., López-Cancio Martínez, E., Amaro, S., Alonso de Leciñana, M., Arenillas, J.F., Ayo-Martín, O., Castellanos, M., Freijo, M.M., García Pastor, A., Gomis, M., Martínez Sánchez, P., Morales, A., Palacio-Portilla, E.J., Roquer, Jaume, Segura, Tomás, Serena, Joaquín, Vivancos-Mora, J., Fuentes Gimeno, Blanca Eulalia, Spanish Society of Neurology's Cerebrovascular Disease Study Group
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/52270
Acceso en línea:http://hdl.handle.net/10230/52270
http://dx.doi.org/10.1016/j.nrleng.2020.04.023
Access Level:acceso abierto
Palabra clave:Antihypertensive drugs
Blood pressure
Fármacos antihipertensivos
Ictus
Presión arterial
Prevención
Prevention
Stroke
Descripción
Sumario:Objective: To update the recommendations of the Spanish Society of Neurology on primary and secondary stroke prevention in patients with arterial hypertension. Development: We proposed several questions to identify practical issues for the management of blood pressure (BP) in stroke prevention, analysing the objectives of blood pressure control, which drugs are most appropriate in primary prevention, when antihypertensive treatment should be started after a stroke, what levels we should aim to achieve, and which drugs are most appropriate in secondary stroke prevention. We conducted a systematic review of the PubMed database and analysed the main clinical trials to address these questions and establish a series of recommendations. Conclusions: In primary stroke prevention, antihypertensive treatment should be started in patients with BP levels > 140/90 mmHg, with a target BP of < 130/80 mmHg. In secondary stroke prevention, we recommend starting antihypertensive treatment after the acute phase (first 24 hours), with a target BP of < 130/80 mmHg. The use of angiotensin-II receptor antagonists or diuretics alone or in combination with angiotensin-converting enzyme inhibitors is preferable.