Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patients

Some of the anatomical and functional basis of cognitive impairment in multiple sclerosis (MS) currently remains unknown. In particular, there is scarce knowledge about modulations in induced EEG (nonphase activity) for diverse frequency bands related to attentional defcits in this pathology. The pr...

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Detalles Bibliográficos
Autores: Vázquez Marrufo, Manuel, Sarrias Arrabal, Esteban, Martín Clemente, Rubén, Galvao Carmona, Alejandro, Navarro, G., Izquierdo, Guillermo
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad Loyola Andalucía
Repositorio:Brújula
OAI Identifier:oai:repositorio.uloyola.es:20.500.12412/4743
Acceso en línea:https://hdl.handle.net/20.500.12412/4743
Access Level:acceso abierto
Palabra clave:Altered phase
Nonphase
EEG
Spatial-object
Multiple sclerosis patients
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spelling Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patientsVázquez Marrufo, ManuelSarrias Arrabal, EstebanMartín Clemente, RubénGalvao Carmona, AlejandroNavarro, G.Izquierdo, GuillermoAltered phaseNonphaseEEGSpatial-objectMultiple sclerosis patientsSome of the anatomical and functional basis of cognitive impairment in multiple sclerosis (MS) currently remains unknown. In particular, there is scarce knowledge about modulations in induced EEG (nonphase activity) for diverse frequency bands related to attentional defcits in this pathology. The present study analyzes phase and nonphase alpha and gamma modulations in 26 remittingrelapsing multiple sclerosis patients during their participation in the attention network test compared with twenty-six healthy controls (HCs) matched in sociodemographic variables. Behavioral results showed that the MS group exhibited general slowing, suggesting impairment in alerting and orienting networks, as has been previously described in other studies. Time–frequency analysis of EEG revealed that the gamma band was related to the spatial translation of the attentional focus, and the alpha band seemed to be related to the expectancy mechanisms and cognitive processing of the target. Moreover, phase and nonphase modulations difered in their psychophysiological roles and were afected diferently in the MS and HC groups. In summary, nonphase modulations can unveil hidden cognitive mechanisms for phase analysis and complete our knowledge of the neural basis of cognitive impairment in multiple sclerosis pathology.2020info:eu-repo/semantics/articlehttps://hdl.handle.net/20.500.12412/4743reponame:Brújulainstname:Universidad Loyola AndalucíaIngléshttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repositorio.uloyola.es:20.500.12412/47432026-06-24T12:48:37Z
dc.title.none.fl_str_mv Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patients
title Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patients
spellingShingle Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patients
Vázquez Marrufo, Manuel
Altered phase
Nonphase
EEG
Spatial-object
Multiple sclerosis patients
title_short Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patients
title_full Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patients
title_fullStr Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patients
title_full_unstemmed Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patients
title_sort Altered phase and nonphase EEG activity expose impaired maintenance of a spatial-object attentional focus in multiple sclerosis patients
dc.creator.none.fl_str_mv Vázquez Marrufo, Manuel
Sarrias Arrabal, Esteban
Martín Clemente, Rubén
Galvao Carmona, Alejandro
Navarro, G.
Izquierdo, Guillermo
author Vázquez Marrufo, Manuel
author_facet Vázquez Marrufo, Manuel
Sarrias Arrabal, Esteban
Martín Clemente, Rubén
Galvao Carmona, Alejandro
Navarro, G.
Izquierdo, Guillermo
author_role author
author2 Sarrias Arrabal, Esteban
Martín Clemente, Rubén
Galvao Carmona, Alejandro
Navarro, G.
Izquierdo, Guillermo
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Altered phase
Nonphase
EEG
Spatial-object
Multiple sclerosis patients
topic Altered phase
Nonphase
EEG
Spatial-object
Multiple sclerosis patients
description Some of the anatomical and functional basis of cognitive impairment in multiple sclerosis (MS) currently remains unknown. In particular, there is scarce knowledge about modulations in induced EEG (nonphase activity) for diverse frequency bands related to attentional defcits in this pathology. The present study analyzes phase and nonphase alpha and gamma modulations in 26 remittingrelapsing multiple sclerosis patients during their participation in the attention network test compared with twenty-six healthy controls (HCs) matched in sociodemographic variables. Behavioral results showed that the MS group exhibited general slowing, suggesting impairment in alerting and orienting networks, as has been previously described in other studies. Time–frequency analysis of EEG revealed that the gamma band was related to the spatial translation of the attentional focus, and the alpha band seemed to be related to the expectancy mechanisms and cognitive processing of the target. Moreover, phase and nonphase modulations difered in their psychophysiological roles and were afected diferently in the MS and HC groups. In summary, nonphase modulations can unveil hidden cognitive mechanisms for phase analysis and complete our knowledge of the neural basis of cognitive impairment in multiple sclerosis pathology.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.12412/4743
url https://hdl.handle.net/20.500.12412/4743
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Brújula
instname:Universidad Loyola Andalucía
instname_str Universidad Loyola Andalucía
reponame_str Brújula
collection Brújula
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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