Generation of a Sprague-Dawley-GFP rat iPS cell line

We generated a rat iPSC line called ATCi-rSD95 from transgenic Sprague-Dawley GFP fetal fibroblasts. Established ATCi-rSD95 cells present a normal karyotype, silencing of the transgenes and express pluripotency-associated markers. Additionally, ATCi-rSD95 cells are able to form teratoma with differe...

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Detalles Bibliográficos
Autores: Coppiello, G. (Giulia)|||/items/d1d63554-537e-458e-8f86-02ae9264fe14, Abizanda-Sarasa, G. (Gloria)|||/items/1e76a0e3-32d0-424e-b58a-d9ddf7a82ef7, Aguado, N. (Natalia)|||/items/91f7fc9c-3ae9-4e5c-961b-1fef6d1496df, Iglesias, E. (Elena)|||/items/aed3c45d-4029-4a78-a859-88079d8b9664, Iglesias-García, O. (Olalla)|||/items/93424e57-6115-4ea0-bcea-436fa10ec58d, Lo-Nigro, A. (Antonio)|||/items/09bf84fa-4e34-4f9e-9156-4dd22f2937eb, Prosper-Cardoso, F. (Felipe)|||/items/3d1b0b82-06c3-4e63-8280-e903dc4dc0c1, Aranguren-López, X. (Xabier)|||/items/217519c3-f392-48cb-b4c9-87d4e2fd0570
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/121832
Acceso en línea:https://hdl.handle.net/10171/121832
Access Level:acceso abierto
Palabra clave:Sprague-Dawley GFP fetal fibroblasts
Descripción
Sumario:We generated a rat iPSC line called ATCi-rSD95 from transgenic Sprague-Dawley GFP fetal fibroblasts. Established ATCi-rSD95 cells present a normal karyotype, silencing of the transgenes and express pluripotency-associated markers. Additionally, ATCi-rSD95 cells are able to form teratoma with differentiated cells derived from the three germ-layers that maintain the GFP expression.

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