Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review

Premorbid functioning has been related with several clinical features and prognosis of schizophrenia spectrum disorders. Comorbidity with substance use is highly prevalent and usually hinders clinical improvement in this kind of psychiatric disorders. This systematic review analyzes the differences...

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Autores: Prat, Gemma, Marquez Arrico, Julia E., Río Martínez, Laura, Navarro Humanes, José Francisco, Adan Puig, Ana
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/185538
Acceso en línea:https://hdl.handle.net/2445/185538
Access Level:acceso abierto
Palabra clave:Esquizofrènia
Abús de substàncies
Ressenyes sistemàtiques (Investigació mèdica)
Schizophrenia
Substance abuse
Systematic reviews (Medical research)
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spelling Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic reviewPrat, GemmaMarquez Arrico, Julia E.Río Martínez, LauraNavarro Humanes, José FranciscoAdan Puig, AnaEsquizofrèniaAbús de substànciesRessenyes sistemàtiques (Investigació mèdica)SchizophreniaSubstance abuseSystematic reviews (Medical research)Premorbid functioning has been related with several clinical features and prognosis of schizophrenia spectrum disorders. Comorbidity with substance use is highly prevalent and usually hinders clinical improvement in this kind of psychiatric disorders. This systematic review analyzes the differences in the premorbid functioning of subjects with a schizophrenia spectrum disorder with substance use (SSD+, dual psychosis) or without it (SSD-). A systematic review (PRISMA guidelines), including search in electronic databases (MEDLINE, Web of Science, and Cochrane Library), was performed. 118 published works were considered of which only 20 met our inclusion criteria. Although there is a great variability in methodologies, diagnoses included, and substances used, studies using the Premorbid Functioning Scale to assess the academic and/or social domains found that SSD+ subjects had a poorer academic but better social premorbid functioning than those with SSD-. Current evidence is not conclusive, so additional studies are required to integrate intervening factors in order to clarify the clinical implications of premorbid functioning to improve the course and therapeutic response of patients.Elsevier B.V.2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/185538Articles publicats en revistes (Psicologia Clínica i Psicobiologia)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1016/j.pnpbp.2021.110310Progress in Neuro-Psychopharmacology & Biological Psychiatry, 2021, vol. 110, p. 110310https://doi.org/10.1016/j.pnpbp.2021.110310cc-by (c) Prat et al., 2021https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1855382026-05-27T06:46:51Z
dc.title.none.fl_str_mv Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review
title Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review
spellingShingle Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review
Prat, Gemma
Esquizofrènia
Abús de substàncies
Ressenyes sistemàtiques (Investigació mèdica)
Schizophrenia
Substance abuse
Systematic reviews (Medical research)
title_short Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review
title_full Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review
title_fullStr Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review
title_full_unstemmed Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review
title_sort Premorbid functioning in schizophrenia spectrum disorders with comorbid substance use: A systematic review
dc.creator.none.fl_str_mv Prat, Gemma
Marquez Arrico, Julia E.
Río Martínez, Laura
Navarro Humanes, José Francisco
Adan Puig, Ana
author Prat, Gemma
author_facet Prat, Gemma
Marquez Arrico, Julia E.
Río Martínez, Laura
Navarro Humanes, José Francisco
Adan Puig, Ana
author_role author
author2 Marquez Arrico, Julia E.
Río Martínez, Laura
Navarro Humanes, José Francisco
Adan Puig, Ana
author2_role author
author
author
author
dc.subject.none.fl_str_mv Esquizofrènia
Abús de substàncies
Ressenyes sistemàtiques (Investigació mèdica)
Schizophrenia
Substance abuse
Systematic reviews (Medical research)
topic Esquizofrènia
Abús de substàncies
Ressenyes sistemàtiques (Investigació mèdica)
Schizophrenia
Substance abuse
Systematic reviews (Medical research)
description Premorbid functioning has been related with several clinical features and prognosis of schizophrenia spectrum disorders. Comorbidity with substance use is highly prevalent and usually hinders clinical improvement in this kind of psychiatric disorders. This systematic review analyzes the differences in the premorbid functioning of subjects with a schizophrenia spectrum disorder with substance use (SSD+, dual psychosis) or without it (SSD-). A systematic review (PRISMA guidelines), including search in electronic databases (MEDLINE, Web of Science, and Cochrane Library), was performed. 118 published works were considered of which only 20 met our inclusion criteria. Although there is a great variability in methodologies, diagnoses included, and substances used, studies using the Premorbid Functioning Scale to assess the academic and/or social domains found that SSD+ subjects had a poorer academic but better social premorbid functioning than those with SSD-. Current evidence is not conclusive, so additional studies are required to integrate intervening factors in order to clarify the clinical implications of premorbid functioning to improve the course and therapeutic response of patients.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/185538
url https://hdl.handle.net/2445/185538
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1016/j.pnpbp.2021.110310
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 2021, vol. 110, p. 110310
https://doi.org/10.1016/j.pnpbp.2021.110310
dc.rights.none.fl_str_mv cc-by (c) Prat et al., 2021
https://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Prat et al., 2021
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Articles publicats en revistes (Psicologia Clínica i Psicobiologia)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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