Integrative cancer genomics (IntOGen) in Biomart

Recently, we created IntOGen, a resource to integrate a large amount of cancer genomic data. IntOGen aims at facilitating the detection of the most recurrent alterations that drive tumorigenesis. It collates, annotates and analyzes high-throughput data about transcriptional, genomic and mutational c...

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Detalles Bibliográficos
Autores: Pérez Llamas, Christian, 1976-, Gundem, Gunes, López Bigas, Núria
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/25449
Acceso en línea:http://hdl.handle.net/10230/25449
http://dx.doi.org/10.1093/database/bar039
Access Level:acceso abierto
Palabra clave:Genòmica
RNA missatger
Bases de dades
Descripción
Sumario:Recently, we created IntOGen, a resource to integrate a large amount of cancer genomic data. IntOGen aims at facilitating the detection of the most recurrent alterations that drive tumorigenesis. It collates, annotates and analyzes high-throughput data about transcriptional, genomic and mutational changes taking place in tumors from different studies annotated with specific cancer types. Currently, it contains 118 studies for mRNA expression profiling and 188 studies for genomic alterations covering in total 64 different tumor topographies. In this article, we describe the Biomart portal for IntOGen. The portal provides easy access to different types of data and facilitates the bulk download of all the analysis results. Here, we describe the general features of IntOGen and give example queries to demonstrate its use. Database URL: www.intogen.org.