A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits

Melon is an economically important fruit crop that has been cultivated for thousands of years; however, the genetic basis and history of its domestication still remain largely unknown. Here we report a comprehensive map of the genomic variation in melon derived from the resequencing of 1,175 accessi...

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Autores: Zhao, Guangwei, Lian, Qun, Zhang, Zhonghua, Fu, Qiushi, He, Yuhua, Ma, Shuangwu, Ruggieri, Valentino, Monforte, Antonio J., Wang, Pingyong, Julca, Irene, Wang, Huaisong, Liu, Junpu, Xu, Yong, Wang, Runze, Ji, Jiabing, Xu, Zhihong, Kong, Weihu, Zhong, Yang, Shang, Jianli, Pereira, Lara, Argyris, Jason, Zhang, Jian, Mayobre, Carlos, Pujol, Marta, Oren, Elad, Ou, Diandian, Wang, Jiming, Sun, Dexi, Zhao, Shengjie, Zhu, Yingchun, Li, Na, Katzir, Nurit, Gur, Amit, Dogimont, Catherine, Schaefer, Hanno, Fan, Wei, Bendahmane, Abdelhafid, Fei, Zhangjun, Pitrat, Michel, Gabaldón, Toni, Lin, Tao, García-Mas, Jordi, Xu, Yongyang, Huang, Sanwen
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/207002
Acceso en línea:http://hdl.handle.net/10261/207002
Access Level:acceso abierto
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spelling A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traitsZhao, GuangweiLian, QunZhang, ZhonghuaFu, QiushiHe, YuhuaMa, ShuangwuRuggieri, ValentinoMonforte, Antonio J.Wang, PingyongJulca, IreneWang, HuaisongLiu, JunpuXu, YongWang, RunzeJi, JiabingXu, ZhihongKong, WeihuZhong, YangShang, JianliPereira, LaraArgyris, JasonZhang, JianMayobre, CarlosPujol, MartaOren, EladOu, DiandianWang, JimingSun, DexiZhao, ShengjieZhu, YingchunLi, NaKatzir, NuritGur, AmitDogimont, CatherineSchaefer, HannoFan, WeiBendahmane, AbdelhafidFei, ZhangjunPitrat, MichelGabaldón, ToniLin, TaoGarcía-Mas, JordiXu, YongyangHuang, SanwenMelon is an economically important fruit crop that has been cultivated for thousands of years; however, the genetic basis and history of its domestication still remain largely unknown. Here we report a comprehensive map of the genomic variation in melon derived from the resequencing of 1,175 accessions, which represent the global diversity of the species. Our results suggest that three independent domestication events occurred in melon, two in India and one in Africa. We detected two independent sets of domestication sweeps, resulting in diverse characteristics of the two subspecies melo and agrestis during melon breeding. Genome-wide association studies for 16 agronomic traits identified 208 loci significantly associated with fruit mass, quality and morphological characters. This study sheds light on the domestication history of melon and provides a valuable resource for genomics-assisted breeding of this important crop.This work was supported by funding from the Agricultural Science and Technology Innovation Program (to Yongyang Xu, S.H., Z.Z. and H.W.), the China Agriculture Research System (CARS-25 to Yongyang Xu and H.W.), the Leading Talents of Guangdong Province Program (00201515 to S.H.), the Shenzhen Municipal (The Peacock Plan KQTD2016113010482651 to S.H.), the Dapeng district government, National Natural Science Foundation of China (31772304 to Z.Z.), the Science and Technology Program of Guangdong (2018B020202007 to S.H.), the National Natural Science Foundation of China (31530066 to S.H.), the National Key R&D Program of China (2016YFD0101007 to S.H.), USDA National Institute of Food and Agriculture Specialty Crop Research Initiative (2015-51181-24285 to Z.F.), the European Research Council (ERC-SEXYPARTH to A.B.), the Spanish Ministry of Economy and Competitiveness (AGL2015–64625-C2-1-R to J.G.-M.), Severo Ochoa Programme for Centres of Excellence in R&D 2016–2010 (SEV-2015–0533 to J.G.-M.), the CERCA Programme/Generalitat de Catalunya to J.G.-M. and the German Science Foundation (SPP1991 Taxon-OMICS to H.S.).Springer NatureAgriculture Research System of ChinaGuandong Academy Of Agricultural SciencesNational Natural Science Foundation of ChinaNational Key Research and Development Program (China)National Institute of Food and Agriculture (US)European Research CouncilMinisterio de Economía y Competitividad (España)Generalitat de CatalunyaGerman Research FoundationConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2020202020192020info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/207002reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/EC/FP7/341076info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2015-64625-C2-1-Rhttps://doi.org/10.1038/s41588-019-0522-8Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2070022026-05-22T06:33:51Z
dc.title.none.fl_str_mv A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits
title A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits
spellingShingle A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits
Zhao, Guangwei
title_short A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits
title_full A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits
title_fullStr A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits
title_full_unstemmed A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits
title_sort A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits
dc.creator.none.fl_str_mv Zhao, Guangwei
Lian, Qun
Zhang, Zhonghua
Fu, Qiushi
He, Yuhua
Ma, Shuangwu
Ruggieri, Valentino
Monforte, Antonio J.
Wang, Pingyong
Julca, Irene
Wang, Huaisong
Liu, Junpu
Xu, Yong
Wang, Runze
Ji, Jiabing
Xu, Zhihong
Kong, Weihu
Zhong, Yang
Shang, Jianli
Pereira, Lara
Argyris, Jason
Zhang, Jian
Mayobre, Carlos
Pujol, Marta
Oren, Elad
Ou, Diandian
Wang, Jiming
Sun, Dexi
Zhao, Shengjie
Zhu, Yingchun
Li, Na
Katzir, Nurit
Gur, Amit
Dogimont, Catherine
Schaefer, Hanno
Fan, Wei
Bendahmane, Abdelhafid
Fei, Zhangjun
Pitrat, Michel
Gabaldón, Toni
Lin, Tao
García-Mas, Jordi
Xu, Yongyang
Huang, Sanwen
author Zhao, Guangwei
author_facet Zhao, Guangwei
Lian, Qun
Zhang, Zhonghua
Fu, Qiushi
He, Yuhua
Ma, Shuangwu
Ruggieri, Valentino
Monforte, Antonio J.
Wang, Pingyong
Julca, Irene
Wang, Huaisong
Liu, Junpu
Xu, Yong
Wang, Runze
Ji, Jiabing
Xu, Zhihong
Kong, Weihu
Zhong, Yang
Shang, Jianli
Pereira, Lara
Argyris, Jason
Zhang, Jian
Mayobre, Carlos
Pujol, Marta
Oren, Elad
Ou, Diandian
Wang, Jiming
Sun, Dexi
Zhao, Shengjie
Zhu, Yingchun
Li, Na
Katzir, Nurit
Gur, Amit
Dogimont, Catherine
Schaefer, Hanno
Fan, Wei
Bendahmane, Abdelhafid
Fei, Zhangjun
Pitrat, Michel
Gabaldón, Toni
Lin, Tao
García-Mas, Jordi
Xu, Yongyang
Huang, Sanwen
author_role author
author2 Lian, Qun
Zhang, Zhonghua
Fu, Qiushi
He, Yuhua
Ma, Shuangwu
Ruggieri, Valentino
Monforte, Antonio J.
Wang, Pingyong
Julca, Irene
Wang, Huaisong
Liu, Junpu
Xu, Yong
Wang, Runze
Ji, Jiabing
Xu, Zhihong
Kong, Weihu
Zhong, Yang
Shang, Jianli
Pereira, Lara
Argyris, Jason
Zhang, Jian
Mayobre, Carlos
Pujol, Marta
Oren, Elad
Ou, Diandian
Wang, Jiming
Sun, Dexi
Zhao, Shengjie
Zhu, Yingchun
Li, Na
Katzir, Nurit
Gur, Amit
Dogimont, Catherine
Schaefer, Hanno
Fan, Wei
Bendahmane, Abdelhafid
Fei, Zhangjun
Pitrat, Michel
Gabaldón, Toni
Lin, Tao
García-Mas, Jordi
Xu, Yongyang
Huang, Sanwen
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
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author
author
author
author
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author
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dc.contributor.none.fl_str_mv Agriculture Research System of China
Guandong Academy Of Agricultural Sciences
National Natural Science Foundation of China
National Key Research and Development Program (China)
National Institute of Food and Agriculture (US)
European Research Council
Ministerio de Economía y Competitividad (España)
Generalitat de Catalunya
German Research Foundation
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
description Melon is an economically important fruit crop that has been cultivated for thousands of years; however, the genetic basis and history of its domestication still remain largely unknown. Here we report a comprehensive map of the genomic variation in melon derived from the resequencing of 1,175 accessions, which represent the global diversity of the species. Our results suggest that three independent domestication events occurred in melon, two in India and one in Africa. We detected two independent sets of domestication sweeps, resulting in diverse characteristics of the two subspecies melo and agrestis during melon breeding. Genome-wide association studies for 16 agronomic traits identified 208 loci significantly associated with fruit mass, quality and morphological characters. This study sheds light on the domestication history of melon and provides a valuable resource for genomics-assisted breeding of this important crop.
publishDate 2019
dc.date.none.fl_str_mv 2019
2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/207002
url http://hdl.handle.net/10261/207002
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/EC/FP7/341076
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2015-64625-C2-1-R
https://doi.org/10.1038/s41588-019-0522-8

dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
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