Detection of saffron adulteration with gardenia extracts through the determination of geniposide by liquid chromatography-mass spectrometry

A new and sophisticated saffron adulteration method with gardenia was recently discovered in the European saffron market. In this work, an analytical methodology using liquid chromatography (quadrupole-time of flight)-mass spectrometry has been developed for the detection of the adulteration of saff...

Descripción completa

Detalles Bibliográficos
Autores: Guijarro Díez, Miguel, Castro Puyana, María|||0000-0003-1412-4103, Crego Navazo, Antonio Luis|||0000-0002-4083-5294, Marina Alegre, María Luisa|||0000-0002-5583-1624
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/48165
Acceso en línea:http://hdl.handle.net/10017/48165
https://dx.doi.org/10.1016/j.jfca.2016.11.004
Access Level:acceso abierto
Palabra clave:Adulteration marker
Geniposide
Gardenia
Liquid chromatography-mass spectrometry
QTOF
Quality control
Saffron
Food analysis
Food composition
Química
Chemistry
Descripción
Sumario:A new and sophisticated saffron adulteration method with gardenia was recently discovered in the European saffron market. In this work, an analytical methodology using liquid chromatography (quadrupole-time of flight)-mass spectrometry has been developed for the detection of the adulteration of saffron samples with gardenia through the determination of geniposide as an adulteration marker. A fused-core C18 column was employed using an isocratic elution with water:acetonitrile (85:15 v/v) containing 0.1% formic acid. After optimization of the mass spectrometry conditions, the analytical characteristics related to the determination of geniposide in negative electrospray ionization mode were evaluated. Then, it was possible to detect up to 10 ng/mL geniposide after a dilution step of 50-fold of the saffron extract (LOD of 41.7 mu g of geniposide per gram of sample analysed (i.e up to 0.004%)). The developed LC-MS methodology was applied to the analysis of different authentic and suspicious saffron samples. (C) 2016 Elsevier Inc. All rights reserved.