Genotypic anomaly in Ebola virus strains circulating in Magazine Wharf area, Freetown, Sierra Leone, 2015.

The Magazine Wharf area, Freetown, Sierra Leone was a focus of ongoing Ebola virus transmission from late June 2015. Viral genomes linked to this area contain a series of 13 T to C substitutions in a 150 base pair intergenic region downstream of viral protein 40 open reading frame, similar to the Eb...

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Detalles Bibliográficos
Autores: Smits , Sl, Pas , Sd, Reusken , Cb, Haagmans , Bl, Pertile , P, Cancedda , C, Dierberg , K, Wurie , I, Kamara , A, Kargbo , D, Caddy , Sarah L, Arias Esteban, Armando, Thorne , Lucy, Lu , Jia, Jah , U, Goodfellow , Ian, Koopmans , Marion P
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Universidad de Castilla-La Mancha
Repositorio:RUIdeRA. Repositorio Institucional de la UCLM
OAI Identifier:oai:ruidera.uclm.es:10578/46907
Acceso en línea:https://hdl.handle.net/10578/46907
Access Level:acceso abierto
Palabra clave:Ebola virus
Epidemiology
Sierra Leona
Descripción
Sumario:The Magazine Wharf area, Freetown, Sierra Leone was a focus of ongoing Ebola virus transmission from late June 2015. Viral genomes linked to this area contain a series of 13 T to C substitutions in a 150 base pair intergenic region downstream of viral protein 40 open reading frame, similar to the Ebolavirus/H.sapienswt/SLE/2014/Makona-J0169 strain (J0169) detected in the same town in November 2014. This suggests that recently circulating viruses from Freetown descend from a J0169-like virus.

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