Trends in the design and use of elastin-like recombinamers as biomaterials

Producción Científica

Detalles Bibliográficos
Autores: Ibáñez Fonseca, Arturo, Flora, Tatjana, Acosta Rodríguez, Sergio, Rodríguez Cabello, José Carlos
Tipo de recurso: artículo
Estado:Versión enviada para evaluación y publicación
Fecha de publicación:2019
País:España
Institución:Universidad de Valladolid
Repositorio:UVaDOC. Repositorio Documental de la Universidad de Valladolid
OAI Identifier:oai:uvadoc.uva.es:10324/40373
Acceso en línea:https://doi.org/10.1016/j.matbio.2019.07.003
http://uvadoc.uva.es/handle/10324/40373
Access Level:acceso abierto
Palabra clave:Biomaterials
Biomateriales
Elastin-like recombinamers
Recombinantes tipo elastina
Intrinsically disordered proteins
Proteínas intrínsecamente desestructuradas
Drug delivery
Administración de medicamentos
Tissue engineering
Ingeniería de tejidos
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spelling Trends in the design and use of elastin-like recombinamers as biomaterialsIbáñez Fonseca, ArturoFlora, TatjanaAcosta Rodríguez, SergioRodríguez Cabello, José CarlosBiomaterialsBiomaterialesElastin-like recombinamersRecombinantes tipo elastinaIntrinsically disordered proteinsProteínas intrínsecamente desestructuradasDrug deliveryAdministración de medicamentosTissue engineeringIngeniería de tejidosProducción CientíficaElastin-like recombinamers (ELRs), which derive from one of the repetitive domains found in natural elastin, have been intensively studied in the last few years from several points of view. In this mini review, we discuss all the recent works related to the investigation of ELRs, starting with those that define these polypeptides as model intrinsically disordered proteins or regions (IDPs or IDRs) and its relevance for some biomedical applications. Furthermore, we summarize the current knowledge on the development of drug, vaccine and gene delivery systems based on ELRs, while also emphasizing the use of ELR-based hydrogels in tissue engineering and regenerative medicine (TERM). Finally, we show different studies that explore applications in other fields, and several examples that describe biomaterial blends in which ELRs have a key role. This review aims to give an overview of the recent advances regarding ELRs and to encourage further investigation of their properties and applications.Comisión Europea (project NMP-2014-646075)Ministerio de Economía, Industria y Competitividad (projects PCIN-2015-010 / MAT2016-78903-R / BES-2014-069763)Junta de Castilla y León (project VA317P18)Elsevier2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/submittedVersionapplication/pdfhttps://doi.org/10.1016/j.matbio.2019.07.003http://uvadoc.uva.es/handle/10324/40373reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolidinstname:Universidad de ValladolidIngléshttps://www.sciencedirect.com/science/article/pii/S0945053X19301520info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/oai:uvadoc.uva.es:10324/403732026-06-13T12:44:47Z
dc.title.none.fl_str_mv Trends in the design and use of elastin-like recombinamers as biomaterials
title Trends in the design and use of elastin-like recombinamers as biomaterials
spellingShingle Trends in the design and use of elastin-like recombinamers as biomaterials
Ibáñez Fonseca, Arturo
Biomaterials
Biomateriales
Elastin-like recombinamers
Recombinantes tipo elastina
Intrinsically disordered proteins
Proteínas intrínsecamente desestructuradas
Drug delivery
Administración de medicamentos
Tissue engineering
Ingeniería de tejidos
title_short Trends in the design and use of elastin-like recombinamers as biomaterials
title_full Trends in the design and use of elastin-like recombinamers as biomaterials
title_fullStr Trends in the design and use of elastin-like recombinamers as biomaterials
title_full_unstemmed Trends in the design and use of elastin-like recombinamers as biomaterials
title_sort Trends in the design and use of elastin-like recombinamers as biomaterials
dc.creator.none.fl_str_mv Ibáñez Fonseca, Arturo
Flora, Tatjana
Acosta Rodríguez, Sergio
Rodríguez Cabello, José Carlos
author Ibáñez Fonseca, Arturo
author_facet Ibáñez Fonseca, Arturo
Flora, Tatjana
Acosta Rodríguez, Sergio
Rodríguez Cabello, José Carlos
author_role author
author2 Flora, Tatjana
Acosta Rodríguez, Sergio
Rodríguez Cabello, José Carlos
author2_role author
author
author
dc.subject.none.fl_str_mv Biomaterials
Biomateriales
Elastin-like recombinamers
Recombinantes tipo elastina
Intrinsically disordered proteins
Proteínas intrínsecamente desestructuradas
Drug delivery
Administración de medicamentos
Tissue engineering
Ingeniería de tejidos
topic Biomaterials
Biomateriales
Elastin-like recombinamers
Recombinantes tipo elastina
Intrinsically disordered proteins
Proteínas intrínsecamente desestructuradas
Drug delivery
Administración de medicamentos
Tissue engineering
Ingeniería de tejidos
description Producción Científica
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/submittedVersion
format article
status_str submittedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1016/j.matbio.2019.07.003
http://uvadoc.uva.es/handle/10324/40373
url https://doi.org/10.1016/j.matbio.2019.07.003
http://uvadoc.uva.es/handle/10324/40373
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://www.sciencedirect.com/science/article/pii/S0945053X19301520
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname:Universidad de Valladolid
instname_str Universidad de Valladolid
reponame_str UVaDOC. Repositorio Documental de la Universidad de Valladolid
collection UVaDOC. Repositorio Documental de la Universidad de Valladolid
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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