Efectos de la ranitidina sobre células parietales en regeneración : Estudio estereológico

In this work, we have carried out a stereological and morphological study in order to verify the effects of Ranitidine on regenerating parietal cells. We have used a control group and operated or non-operated groups treated with 2, 10 and 50 mg/kglday Ranitidine. In operated groups an ulcer was prov...

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Detalhes bibliográficos
Autores: Torreblanca López, José, Ibáñez Delgado, Francisco, López Campos, José Luis, Moreno Onorato, Francisco Javier
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:1990
País:España
Recursos:Universidad de Sevilla (US)
Repositório:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/40657
Acesso em linha:http://hdl.handle.net/11441/40657
Access Level:Acceso aberto
Palavra-chave:Parietal cells
Stereological study
Ranitidina
Ranitidine
Célula parietal
Estudio estereológico
Descrição
Resumo:In this work, we have carried out a stereological and morphological study in order to verify the effects of Ranitidine on regenerating parietal cells. We have used a control group and operated or non-operated groups treated with 2, 10 and 50 mg/kglday Ranitidine. In operated groups an ulcer was provoked by cauterization with a metallic plate in the gastric fundus. Groups treated with high doses of Ranitidine showed an increase in the connective tissue of the gastrlc mucosa. The stereological study in treated groups shows a decrease in the parietal voiume density, and an increase in the cellular profile. Changes detected in the parietal volume density would originate a decrease in the production of CIH