Development of high-resolution 3D printable polymerizable ionic liquids for antimicrobial applications
[The bigger picture] In the quest to address global antibiotic resistance, this study pioneers 3D-printable antimicrobial polymeric scaffolds with embedded copper-based nanoparticles. A polymeric formulation based on polymeric ionic liquids has been carefully designed to overcome nanoparticle stabil...
| Autores: | , , , , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/354438 |
| Acesso em linha: | http://hdl.handle.net/10261/354438 |
| Access Level: | acceso abierto |
| Palavra-chave: | 3D printing Biocompatible Polymerizable ionic liquids Additive manufacturing Antimicrobials Digital light processing Stereolithography |
| Resumo: | [The bigger picture] In the quest to address global antibiotic resistance, this study pioneers 3D-printable antimicrobial polymeric scaffolds with embedded copper-based nanoparticles. A polymeric formulation based on polymeric ionic liquids has been carefully designed to overcome nanoparticle stabilization challenges, while being optimized for 3D printing. Customized formulations for digital light processing and masked stereolithography-based 3D printing are introduced, resulting in high-resolution materials with potent antimicrobial properties. Successful 3D printing of a device analogous to a medical stent demonstrated their efficacy against the growth of S. epidermidis bacteria. This research underscores additive manufacturing’s transformative potential for high-resolution devices, contributing significantly to a critical global health concern. It establishes a foundation for diverse antimicrobial solutions, marking a substantial advancement in the field. |
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