Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, Pakistan

Infectious keratoconjunctivitis (IKC) is a contagious eye disease primarily caused by Mycoplasma conjunctivae in domestic and wild Caprinae. Chlamydophila species have also been detected in ruminants with IKC. The objectives of this study are to investigate the ocular infection of M. conjunctivae an...

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Autores: Fernández Aguilar, Xavier|||0000-0002-4939-6048, Rossi, Luca|||0000-0001-6829-5229, Cabezón Ponsoda, Óscar|||0000-0001-7543-8371, Giorgino, Andrea, Victoriano Llopis, Isis, Frey, Joachim|||0000-0001-9133-0280, López Olvera, Jorge R.|||0000-0002-2999-3451
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:186303
Acceso en línea:https://ddd.uab.cat/record/186303
https://dx.doi.org/urn:doi:10.1136/vr.103948
Access Level:acceso abierto
Palabra clave:Chlamydophila pecorum
Coinfection
Goat
Infectious keratoconjunctivitis
Sheep
Wildlife livestock interface
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spelling Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, PakistanFernández Aguilar, Xavier|||0000-0002-4939-6048Rossi, Luca|||0000-0001-6829-5229Cabezón Ponsoda, Óscar|||0000-0001-7543-8371Giorgino, AndreaVictoriano Llopis, IsisFrey, Joachim|||0000-0001-9133-0280López Olvera, Jorge R.|||0000-0002-2999-3451Chlamydophila pecorumCoinfectionGoatInfectious keratoconjunctivitisSheepWildlife livestock interfaceInfectious keratoconjunctivitis (IKC) is a contagious eye disease primarily caused by Mycoplasma conjunctivae in domestic and wild Caprinae. Chlamydophila species have also been detected in ruminants with IKC. The objectives of this study are to investigate the ocular infection of M. conjunctivae and Chlamydiaceae and assess its interaction in relation to IKC in sheep and goats from remote communities around the Central Karakoram National Park in Pakistan, performing a combination of cross-sectional and case-control study design. Mostly asymptomatic and endemic infections of M. conjunctivae and Chlamydiaceae were found in sheep (19.3 per cent and 4.5 per cent, respectively) and goats (9.5 per cent and 1.9 per cent, respectively) from all communities, assessed by qPCR. Prevalence significantly differed between species only for M. conjunctivae (P=0.0184), which was also more prevalent in younger sheep (P<0.01). Chlamydophila pecorum was identified by sequencing and was related with IKC only when coinfection with M. conjunctivae occurred, which suggest a synergic interaction. Cluster analysis of M. conjunctivae strains revealed higher diversity of strains than expected, evidenced interspecific transmission and suggested a higher local livestock trade than previously assumed. These results highlight the widespread occurrence of M conjunctivae in sheep worldwide and its implications for wildlife should be assessed from a conservation perspective. 22017-01-0120172017-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/186303https://dx.doi.org/urn:doi:10.1136/vr.103948reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre i quan aquestes es distribueixin sota la mateixa llicència que regula l'obra original i es reconegui l'autoria.https://creativecommons.org/licenses/by-sa/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:1863032026-06-06T12:50:31Z
dc.title.none.fl_str_mv Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, Pakistan
title Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, Pakistan
spellingShingle Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, Pakistan
Fernández Aguilar, Xavier|||0000-0002-4939-6048
Chlamydophila pecorum
Coinfection
Goat
Infectious keratoconjunctivitis
Sheep
Wildlife livestock interface
title_short Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, Pakistan
title_full Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, Pakistan
title_fullStr Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, Pakistan
title_full_unstemmed Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, Pakistan
title_sort Infectious keratoconjunctivitis and occurrence of Mycoplasma conjunctivae and Chlamydiaceae in small domestic ruminants from Central Karakoram, Pakistan
dc.creator.none.fl_str_mv Fernández Aguilar, Xavier|||0000-0002-4939-6048
Rossi, Luca|||0000-0001-6829-5229
Cabezón Ponsoda, Óscar|||0000-0001-7543-8371
Giorgino, Andrea
Victoriano Llopis, Isis
Frey, Joachim|||0000-0001-9133-0280
López Olvera, Jorge R.|||0000-0002-2999-3451
author Fernández Aguilar, Xavier|||0000-0002-4939-6048
author_facet Fernández Aguilar, Xavier|||0000-0002-4939-6048
Rossi, Luca|||0000-0001-6829-5229
Cabezón Ponsoda, Óscar|||0000-0001-7543-8371
Giorgino, Andrea
Victoriano Llopis, Isis
Frey, Joachim|||0000-0001-9133-0280
López Olvera, Jorge R.|||0000-0002-2999-3451
author_role author
author2 Rossi, Luca|||0000-0001-6829-5229
Cabezón Ponsoda, Óscar|||0000-0001-7543-8371
Giorgino, Andrea
Victoriano Llopis, Isis
Frey, Joachim|||0000-0001-9133-0280
López Olvera, Jorge R.|||0000-0002-2999-3451
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Chlamydophila pecorum
Coinfection
Goat
Infectious keratoconjunctivitis
Sheep
Wildlife livestock interface
topic Chlamydophila pecorum
Coinfection
Goat
Infectious keratoconjunctivitis
Sheep
Wildlife livestock interface
description Infectious keratoconjunctivitis (IKC) is a contagious eye disease primarily caused by Mycoplasma conjunctivae in domestic and wild Caprinae. Chlamydophila species have also been detected in ruminants with IKC. The objectives of this study are to investigate the ocular infection of M. conjunctivae and Chlamydiaceae and assess its interaction in relation to IKC in sheep and goats from remote communities around the Central Karakoram National Park in Pakistan, performing a combination of cross-sectional and case-control study design. Mostly asymptomatic and endemic infections of M. conjunctivae and Chlamydiaceae were found in sheep (19.3 per cent and 4.5 per cent, respectively) and goats (9.5 per cent and 1.9 per cent, respectively) from all communities, assessed by qPCR. Prevalence significantly differed between species only for M. conjunctivae (P=0.0184), which was also more prevalent in younger sheep (P<0.01). Chlamydophila pecorum was identified by sequencing and was related with IKC only when coinfection with M. conjunctivae occurred, which suggest a synergic interaction. Cluster analysis of M. conjunctivae strains revealed higher diversity of strains than expected, evidenced interspecific transmission and suggested a higher local livestock trade than previously assumed. These results highlight the widespread occurrence of M conjunctivae in sheep worldwide and its implications for wildlife should be assessed from a conservation perspective.
publishDate 2017
dc.date.none.fl_str_mv 2
2017-01-01
2017
2017-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/186303
https://dx.doi.org/urn:doi:10.1136/vr.103948
url https://ddd.uab.cat/record/186303
https://dx.doi.org/urn:doi:10.1136/vr.103948
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-sa/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-sa/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
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