The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margin

Background: Whereas the usefulness of radiofrequency (RF) energy as haemostatic method in liver surgery has become well established in the last decades, its intentional application on resection margins with the aim of reducing local recurrence is still debatable. Our goal was to compare the impact o...

Descripción completa

Detalles Bibliográficos
Autores: Villamonte, María, Burdío, Fernando|||0000-0003-3038-0086, Pueyo, Eva, Andaluz Martínez, Anna|||0000-0001-8097-8110, Moll, Xavier|||0000-0002-2992-9361, Berjano, Enrique|||0000-0002-3247-2665, Radosevic, Aleksander, Grande, L|||0000-0001-9146-9004, Pera, Miguel|||0000-0001-7764-6481, Ielpo, Benedetto|||0000-0003-3129-3208, Sánchez-Velázquez, Patricia|||0000-0002-7902-3920
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:308637
Acceso en línea:https://ddd.uab.cat/record/308637
https://dx.doi.org/urn:doi:10.1016/j.ejso.2021.06.008
Access Level:acceso abierto
Palabra clave:Liver Recurrence
Margin invasion
Radiofrequency ablation
id ES_8b6be27ddecbbf52d99b9e495eca20ff
oai_identifier_str oai:ddd.uab.cat:308637
network_acronym_str ES
network_name_str España
repository_id_str
spelling The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margincan we improve the oncological results? A propensity score matching studyVillamonte, MaríaBurdío, Fernando|||0000-0003-3038-0086Pueyo, EvaAndaluz Martínez, Anna|||0000-0001-8097-8110Moll, Xavier|||0000-0002-2992-9361Berjano, Enrique|||0000-0002-3247-2665Radosevic, AleksanderGrande, L|||0000-0001-9146-9004Pera, Miguel|||0000-0001-7764-6481Ielpo, Benedetto|||0000-0003-3129-3208Sánchez-Velázquez, Patricia|||0000-0002-7902-3920Liver RecurrenceMargin invasionRadiofrequency ablationBackground: Whereas the usefulness of radiofrequency (RF) energy as haemostatic method in liver surgery has become well established in the last decades, its intentional application on resection margins with the aim of reducing local recurrence is still debatable. Our goal was to compare the impact of an additional application of RF energy on the top of the resection surface, namely additional margin coagulation (AMC), on local recurrence (LR) when subjected to a subcentimeter margin. Methods: We retrospectively analyzed 185 patients out of a whole cohort of 283 patients who underwent radical hepatic resection with subcentimetric margin. After propensity score adjustment, patients were classified into two balanced groups according to whether RF was applied or not. Results: No significant differences were observed within groups in baseline characteristics after PSM adjustment. The LR rate was significantly higher in the Control than AMC Group: 12 patients (14.5%) vs. 4 patients (4.8%) (p = 0.039). The estimated 1, 3, and 5-year LR-free survival rates of patients in the Control and AMC Group were: 93.5%, 86.0%, 81.0% and 98.8%, 97.2%, 91.9%, respectively (p = 0.049). Univariate Cox analyses indicated that the use of the RF applicator was significantly associated with lower LR (HR = 0.29, 95% confidence interval 0.093-0.906, p = 0.033). The Control Group showed smaller coagulation widths than the AMC group (p < 0.001). Conclusions: An additional application of RF on the top of the resection surface is associated with less local hepatic recurrence than the use of conventional techniques. 22022-01-0120222022-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/308637https://dx.doi.org/urn:doi:10.1016/j.ejso.2021.06.008reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengAgencia Estatal de Investigación https://doi.org/10.13039/501100011033 RTI2018-094357-B-C21Agencia Estatal de Investigación https://doi.org/10.13039/501100011033 RTI2018-094357-B-C22open accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3086372026-06-06T12:50:31Z
dc.title.none.fl_str_mv The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margin
can we improve the oncological results? A propensity score matching study
title The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margin
spellingShingle The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margin
Villamonte, María
Liver Recurrence
Margin invasion
Radiofrequency ablation
title_short The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margin
title_full The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margin
title_fullStr The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margin
title_full_unstemmed The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margin
title_sort The impact of additional margin coagulation with radiofrequency in liver resections with subcentimetric margin
dc.creator.none.fl_str_mv Villamonte, María
Burdío, Fernando|||0000-0003-3038-0086
Pueyo, Eva
Andaluz Martínez, Anna|||0000-0001-8097-8110
Moll, Xavier|||0000-0002-2992-9361
Berjano, Enrique|||0000-0002-3247-2665
Radosevic, Aleksander
Grande, L|||0000-0001-9146-9004
Pera, Miguel|||0000-0001-7764-6481
Ielpo, Benedetto|||0000-0003-3129-3208
Sánchez-Velázquez, Patricia|||0000-0002-7902-3920
author Villamonte, María
author_facet Villamonte, María
Burdío, Fernando|||0000-0003-3038-0086
Pueyo, Eva
Andaluz Martínez, Anna|||0000-0001-8097-8110
Moll, Xavier|||0000-0002-2992-9361
Berjano, Enrique|||0000-0002-3247-2665
Radosevic, Aleksander
Grande, L|||0000-0001-9146-9004
Pera, Miguel|||0000-0001-7764-6481
Ielpo, Benedetto|||0000-0003-3129-3208
Sánchez-Velázquez, Patricia|||0000-0002-7902-3920
author_role author
author2 Burdío, Fernando|||0000-0003-3038-0086
Pueyo, Eva
Andaluz Martínez, Anna|||0000-0001-8097-8110
Moll, Xavier|||0000-0002-2992-9361
Berjano, Enrique|||0000-0002-3247-2665
Radosevic, Aleksander
Grande, L|||0000-0001-9146-9004
Pera, Miguel|||0000-0001-7764-6481
Ielpo, Benedetto|||0000-0003-3129-3208
Sánchez-Velázquez, Patricia|||0000-0002-7902-3920
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Liver Recurrence
Margin invasion
Radiofrequency ablation
topic Liver Recurrence
Margin invasion
Radiofrequency ablation
description Background: Whereas the usefulness of radiofrequency (RF) energy as haemostatic method in liver surgery has become well established in the last decades, its intentional application on resection margins with the aim of reducing local recurrence is still debatable. Our goal was to compare the impact of an additional application of RF energy on the top of the resection surface, namely additional margin coagulation (AMC), on local recurrence (LR) when subjected to a subcentimeter margin. Methods: We retrospectively analyzed 185 patients out of a whole cohort of 283 patients who underwent radical hepatic resection with subcentimetric margin. After propensity score adjustment, patients were classified into two balanced groups according to whether RF was applied or not. Results: No significant differences were observed within groups in baseline characteristics after PSM adjustment. The LR rate was significantly higher in the Control than AMC Group: 12 patients (14.5%) vs. 4 patients (4.8%) (p = 0.039). The estimated 1, 3, and 5-year LR-free survival rates of patients in the Control and AMC Group were: 93.5%, 86.0%, 81.0% and 98.8%, 97.2%, 91.9%, respectively (p = 0.049). Univariate Cox analyses indicated that the use of the RF applicator was significantly associated with lower LR (HR = 0.29, 95% confidence interval 0.093-0.906, p = 0.033). The Control Group showed smaller coagulation widths than the AMC group (p < 0.001). Conclusions: An additional application of RF on the top of the resection surface is associated with less local hepatic recurrence than the use of conventional techniques.
publishDate 2022
dc.date.none.fl_str_mv 2
2022-01-01
2022
2022-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/308637
https://dx.doi.org/urn:doi:10.1016/j.ejso.2021.06.008
url https://ddd.uab.cat/record/308637
https://dx.doi.org/urn:doi:10.1016/j.ejso.2021.06.008
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Agencia Estatal de Investigación https://doi.org/10.13039/501100011033 RTI2018-094357-B-C21
Agencia Estatal de Investigación https://doi.org/10.13039/501100011033 RTI2018-094357-B-C22
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869412807689109504
score 15.811543

Similares en LA Referencia