Heteroplasmy, multiple variants of mitochondrial DNA (mtDNA) in the same cytoplasm, may be naturally generated by mutations but is counteracted by a genetic mtDNA bottleneck during oocyte development. Engineered heteroplasmic mice with nonpathological mtDNA variants reveal a nonrandom tissue-specifi...
Detalles Bibliográficos
| Autores: |
Lechuga-Vieco, Ana V.,
Latorre-Pellicer, Ana,
Johnston, Iain G,
Prota, Gennaro,
Gileadi, Uzi,
Justo-Mendez, Raquel,
Acin-Perez, Rebeca,
Martínez-de-Mena, Raquel,
Fernandez-Toro, Jose Maria,
Jimenez-Blasco, Daniel,
Mora, Alfonso,
Nicolas-Avila, Jose A.,
Santiago, Demetrio J,
Priori, Silvia G.,
Bolaños, Juan Pedro,
Sabio, Guadalupe,
Criado-Rodriguez, Luis M.,
Ruiz-Cabello, Jesus,
Cerundolo, Vincenzo,
Jones, Nick S,
Enriquez, Jose Antonio |
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| Tipo de recurso: | artículo
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| Fecha de publicación: | 2020 |
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| País: | España |
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| Institución: | Instituto de Salud Carlos III (ISCIII) |
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| Repositorio: | Repisalud |
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| Idioma: | inglés |
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| OAI Identifier: | oai:repisalud.isciii.es:20.500.12105/11255 |
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| Acceso en línea: | http://hdl.handle.net/20.500.12105/11255
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| Access Level: | acceso abierto |
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