Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy

[EN] Purpose: The purpose of this study is to validate the PenRed Monte Carlo framework for clinical applications in brachytherapy. PenRed is a C++ version of Penelope Monte Carlo code with additional tallies and utilities. Methods and materials: Six benchmarking scenarios are explored to validate t...

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Autores: Oliver-Gil, Sandra|||0000-0001-8258-3972, Giménez-Alventosa, Vicent|||0000-0003-1646-6094, Berumen, F., Giménez, V., Beaulieu, L., Ballester, F., Vijande, J.
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/201514
Acceso en línea:https://riunet.upv.es/handle/10251/201514
Access Level:acceso abierto
Palabra clave:Monte Carlo
PenRed
Brachytherapy
DICOM
Medical physics
FISICA APLICADA
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oai_identifier_str oai:riunet.upv.es:10251/201514
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy
title Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy
spellingShingle Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy
Oliver-Gil, Sandra|||0000-0001-8258-3972
Monte Carlo
PenRed
Brachytherapy
DICOM
Medical physics
FISICA APLICADA
title_short Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy
title_full Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy
title_fullStr Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy
title_full_unstemmed Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy
title_sort Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy
dc.creator.none.fl_str_mv Oliver-Gil, Sandra|||0000-0001-8258-3972
Giménez-Alventosa, Vicent|||0000-0003-1646-6094
Berumen, F.
Giménez, V.
Beaulieu, L.
Ballester, F.
Vijande, J.
author Oliver-Gil, Sandra|||0000-0001-8258-3972
author_facet Oliver-Gil, Sandra|||0000-0001-8258-3972
Giménez-Alventosa, Vicent|||0000-0003-1646-6094
Berumen, F.
Giménez, V.
Beaulieu, L.
Ballester, F.
Vijande, J.
author_role author
author2 Giménez-Alventosa, Vicent|||0000-0003-1646-6094
Berumen, F.
Giménez, V.
Beaulieu, L.
Ballester, F.
Vijande, J.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Departamento de Física Aplicada
Escuela Técnica Superior de Ingeniería Industrial
Instituto Universitario de Seguridad Industrial, Radiofísica y Medioambiental
Departamento de Estadística e Investigación Operativa Aplicadas y Calidad
Escuela Técnica Superior de Ingeniería Aeroespacial y Diseño Industrial
Generalitat Valenciana
Agencia Estatal de Investigación
Ministerio de Ciencia e Innovación
Fonds de Recherche du Québec - Nature et Technologies
Natural Sciences and Engineering Research Council of Canada
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv Monte Carlo
PenRed
Brachytherapy
DICOM
Medical physics
FISICA APLICADA
topic Monte Carlo
PenRed
Brachytherapy
DICOM
Medical physics
FISICA APLICADA
description [EN] Purpose: The purpose of this study is to validate the PenRed Monte Carlo framework for clinical applications in brachytherapy. PenRed is a C++ version of Penelope Monte Carlo code with additional tallies and utilities. Methods and materials: Six benchmarking scenarios are explored to validate the use of PenRed and its improved bachytherapy-oriented capabilities for HDR brachytherapy. A new tally allowing the evaluation of collisional kerma for any material using the track length kerma estimator and the possibility to obtain the seed positions, weights and directions processing directly the DICOM file are now implemented in the PenRed distribution. The four non-clinical test cases developed by the Joint AAPM-ESTRO-ABG-ABS WG-DCAB were evaluated by comparing local and global absorbed dose differences with respect to established reference datasets. A prostate and a palliative lung cases, were also studied. For them, absorbed dose ratios, global absorbed dose differences, and cumulative dose-volume histograms were obtained and discussed. Results: The air-kerma strength and the dose rate constant corresponding to the two sources agree with the reference datatests within 0.3% (Sk) and 0.1% (¿). With respect to the first three WG-DCAB test cases, more than 99.8% of the voxels present local (global) differences within ±1%(±0.1%) of the reference datasets. For test Case 4 reference dataset, more than 94.9%(97.5%) of voxels show an agreement within ±1%(±0.1%), better than similar benchmarking calculations in the literature. The track length kerma estimator scorer implemented increases the numerical efficiency of brachytherapy calculations two orders of magnitude, while the specific brachytherapy source allows the user to avoid the use of error-prone intermediate steps to translate the DICOM information into the simulation. In both clinical cases, only minor absorbed dose differences arise in the low-dose isodoses. 99.8% and 100% of the voxels have a global absorbed dose difference ratio within ±0.2% for the prostate and lung cases, respectively. The role played by the different segmentation and composition material in the bone structures was discussed, obtaining negligible absorbed dose differences. Dose-volume histograms were in agreement with the reference data. Conclusions: PenRed incorporates new tallies and utilities and has been validated for its use for detailed and precise high-dose-rate brachytherapy simulations.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-11-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/201514
url https://riunet.upv.es/handle/10251/201514
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Agencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 PID2020-113126RB-I00 COMPUTACION CIENTIFICA SERVERLESS A TRAVES DEL HIBRIDO CONTINUO CLOUD
Agencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 PID2020-113334GB-I00 PARTICULAS ELEMENTALES: EL MODELO ESTANDAR Y SUS EXTENSIONES
Natural Sciences and Engineering Research Council of Canada NSERC RGPIN-2019-05038
Generalitat Valenciana https://doi.org/10.13039/501100003359 PROMETEO%2F2019%2F087
Generalitat Valenciana https://doi.org/10.13039/501100003359 PROMETEO%2F2021%2F064
Ministerio de Ciencia e Innovación http://dx.doi.org/10.13039/501100004837 PID2021-125096NB-I00
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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spelling Benchmark of the PenRed Monte Carlo framework for HDR brachytherapyOliver-Gil, Sandra|||0000-0001-8258-3972Giménez-Alventosa, Vicent|||0000-0003-1646-6094Berumen, F.Giménez, V.Beaulieu, L.Ballester, F.Vijande, J.Monte CarloPenRedBrachytherapyDICOMMedical physicsFISICA APLICADA[EN] Purpose: The purpose of this study is to validate the PenRed Monte Carlo framework for clinical applications in brachytherapy. PenRed is a C++ version of Penelope Monte Carlo code with additional tallies and utilities. Methods and materials: Six benchmarking scenarios are explored to validate the use of PenRed and its improved bachytherapy-oriented capabilities for HDR brachytherapy. A new tally allowing the evaluation of collisional kerma for any material using the track length kerma estimator and the possibility to obtain the seed positions, weights and directions processing directly the DICOM file are now implemented in the PenRed distribution. The four non-clinical test cases developed by the Joint AAPM-ESTRO-ABG-ABS WG-DCAB were evaluated by comparing local and global absorbed dose differences with respect to established reference datasets. A prostate and a palliative lung cases, were also studied. For them, absorbed dose ratios, global absorbed dose differences, and cumulative dose-volume histograms were obtained and discussed. Results: The air-kerma strength and the dose rate constant corresponding to the two sources agree with the reference datatests within 0.3% (Sk) and 0.1% (¿). With respect to the first three WG-DCAB test cases, more than 99.8% of the voxels present local (global) differences within ±1%(±0.1%) of the reference datasets. For test Case 4 reference dataset, more than 94.9%(97.5%) of voxels show an agreement within ±1%(±0.1%), better than similar benchmarking calculations in the literature. The track length kerma estimator scorer implemented increases the numerical efficiency of brachytherapy calculations two orders of magnitude, while the specific brachytherapy source allows the user to avoid the use of error-prone intermediate steps to translate the DICOM information into the simulation. In both clinical cases, only minor absorbed dose differences arise in the low-dose isodoses. 99.8% and 100% of the voxels have a global absorbed dose difference ratio within ±0.2% for the prostate and lung cases, respectively. The role played by the different segmentation and composition material in the bone structures was discussed, obtaining negligible absorbed dose differences. Dose-volume histograms were in agreement with the reference data. Conclusions: PenRed incorporates new tallies and utilities and has been validated for its use for detailed and precise high-dose-rate brachytherapy simulations.This work is partially supported by the Ministerio de Ciencia e Innovación of Spain (MCIN) grants PID2020- 113126RB-I00 and PID2021-125096NB-I00 funded by MCIN/AEI/10.13039/501100011033. V. G. acknowledges partial support from AEI-MICINN under grant PID2020-1 13334GB-I00/AEI/10.13039/501100011033 and by Generalitat Valenciana through the project PROMETEO/2019/087. The work has also been supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) grant RGPIN-2019-05038. Francisco Berumen acknowledges support by the Fonds de Recherche du Québec ¿ Nature et Technologies (FRQNT). J.V. and F.B. would like to acknowledge funding by MCIN/ AEI/10.13039 and the Generalitat Valenciana (GVA) grant PROMETEO/2021/064. Our colleague Prof. Vicent Giménez Gómez passed away on November 16, 2022, during the proofs of this study. We dedicate it to his memory. The Universitat de València lost a dedicated and accomplished physicist.ElsevierDepartamento de Física AplicadaEscuela Técnica Superior de Ingeniería IndustrialInstituto Universitario de Seguridad Industrial, Radiofísica y MedioambientalDepartamento de Estadística e Investigación Operativa Aplicadas y CalidadEscuela Técnica Superior de Ingeniería Aeroespacial y Diseño IndustrialGeneralitat ValencianaAgencia Estatal de InvestigaciónMinisterio de Ciencia e InnovaciónFonds de Recherche du Québec - Nature et TechnologiesNatural Sciences and Engineering Research Council of CanadaRepositorio Institucional de la Universitat Politècnica de València Riunet20232023-11-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://riunet.upv.es/handle/10251/201514reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengAgencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 PID2020-113126RB-I00 COMPUTACION CIENTIFICA SERVERLESS A TRAVES DEL HIBRIDO CONTINUO CLOUDAgencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 PID2020-113334GB-I00 PARTICULAS ELEMENTALES: EL MODELO ESTANDAR Y SUS EXTENSIONESNatural Sciences and Engineering Research Council of Canada NSERC RGPIN-2019-05038Generalitat Valenciana https://doi.org/10.13039/501100003359 PROMETEO%2F2019%2F087Generalitat Valenciana https://doi.org/10.13039/501100003359 PROMETEO%2F2021%2F064Ministerio de Ciencia e Innovación http://dx.doi.org/10.13039/501100004837 PID2021-125096NB-I00open accesshttp://purl.org/coar/access_right/c_abf2Reconocimiento (by)http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/2015142026-06-13T07:49:27Z
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