Looking at the periphery—new hypothesis to look for new targets for Alzheimer’s disease therapy

Currently, the predominant targets for the treatment of Alzheimer’s disease (AD) are the main components of the two pathological structures: senile plaques (composed of amyloid beta peptide aggregates) or neurofibrillary tangles (constructed of tau protein polymers). However, the existence of adequa...

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Detalles Bibliográficos
Autores: Avila, Jesús, Pérez, Mar, Avila-Villanueva, Marina, Santa-María, Ismael, Hernández, Félix
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Francisco de Vitoria
Repositorio:DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Idioma:inglés
OAI Identifier:oai:ddfv.ufv.es:10641/7424
Acceso en línea:https://hdl.handle.net/10641/7424
Access Level:acceso abierto
Palabra clave:Alzheimer’s disease
biomarkers
non-neuronal tissues
Neuroscience (miscellaneous)
Cognitive Neuroscience
Neurology
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Descripción
Sumario:Currently, the predominant targets for the treatment of Alzheimer’s disease (AD) are the main components of the two pathological structures: senile plaques (composed of amyloid beta peptide aggregates) or neurofibrillary tangles (constructed of tau protein polymers). However, the existence of adequate disease modifiers based on such targets is discussed. In this special issue, it has been suggested to search for new possible targets for AD therapy. This contribution tries to analyze non-neuronal tissues (periphery) to identify potential factors (target) involved in the development of AD.