Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009

García de Olalla, Patricia|||0000-0002-2293-3560; Manzardo, Christian; Sambeat Doménech, María Antonia; Ocaña Rivera, Immaculada|||0000-0003-3699-0790; Knobel Freud, Hernando|||0000-0003-3186-6416; Humet, Victoria; Domingo Pedrol, Pedro|||0000-0003-1138-5770; Ribera Pascuet, Esteban; Guelar, Ana; Marco, Andrés; Belza, María José|||0000-0003-4816-7750; Miró, José M.|||0000-0001-8057-7755; Caylà, Joan A.|||0000-0003-3891-111X

Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009

Background: Early diagnosis of HIV infection can prevent morbidity and mortality as well as reduce HIV transmission. The aim of the present study was to assess prevalence, describe trends and identify factors associated with late presentation of HIV infection in Barcelona (Spain) during the period 2...

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Autores:	García de Olalla, Patricia\|\|\|0000-0002-2293-3560, Manzardo, Christian, Sambeat Doménech, María Antonia, Ocaña Rivera, Immaculada\|\|\|0000-0003-3699-0790, Knobel Freud, Hernando\|\|\|0000-0003-3186-6416, Humet, Victoria, Domingo Pedrol, Pedro\|\|\|0000-0003-1138-5770, Ribera Pascuet, Esteban, Guelar, Ana, Marco, Andrés, Belza, María José\|\|\|0000-0003-4816-7750, Miró, José M.\|\|\|0000-0001-8057-7755, Caylà, Joan A.\|\|\|0000-0003-3891-111X
Tipo de recurso:	artículo
Fecha de publicación:	2011
País:	España
Institución:	Universitat Autònoma de Barcelona
Repositorio:	Dipòsit Digital de Documents de la UAB
Idioma:	inglés
OAI Identifier:	oai:ddd.uab.cat:112191
Acceso en línea:	https://ddd.uab.cat/record/112191 https://dx.doi.org/urn:doi:10.1186/1742-6405-8-22
Access Level:	acceso abierto
Palabra clave:	HIV infection Late presentation Epidemiology predictors Barcelona Spain

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spelling	Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009García de Olalla, Patricia\|\|\|0000-0002-2293-3560Manzardo, ChristianSambeat Doménech, María AntoniaOcaña Rivera, Immaculada\|\|\|0000-0003-3699-0790Knobel Freud, Hernando\|\|\|0000-0003-3186-6416Humet, VictoriaDomingo Pedrol, Pedro\|\|\|0000-0003-1138-5770Ribera Pascuet, EstebanGuelar, AnaMarco, AndrésBelza, María José\|\|\|0000-0003-4816-7750Miró, José M.\|\|\|0000-0001-8057-7755Caylà, Joan A.\|\|\|0000-0003-3891-111XHIV infectionLate presentationEpidemiology predictorsBarcelonaSpainBackground: Early diagnosis of HIV infection can prevent morbidity and mortality as well as reduce HIV transmission. The aim of the present study was to assess prevalence, describe trends and identify factors associated with late presentation of HIV infection in Barcelona (Spain) during the period 2001-09. Methods: Demographic and epidemiological characteristics of cases reported to the Barcelona HIV surveillance system were analysed. Late presentation was defined for individuals with a CD4 count below 350 cells/ml upon HIV diagnosis or diagnosis of AIDS within 3 months of HIV diagnosis. Multivariate logistic regression were used to identify predictors of late presentation. Results: Of the 2,938 newly diagnosed HIV-infected individuals, 2,507 (85,3%) had either a CD4 cell count or an AIDS diagnosis available. A total of 1,139 (55.6%) of the 2,507 studied cases over these nine years were late presenters varying from 48% among men who have sex with men to 70% among heterosexual men. The proportion of late presentation was 62.7% in 2001-2003, 51.9% in 2004-2005, 52.6% in 2006-2007 and 52.1% in 2008-2009. A decrease over time only was observed between 2001-2003 and 2004-2005 (p = 0.001) but remained constant thereafter (p = 0.9). Independent risk factors for late presentation were older age at diagnosis (p < 0.0001), use of injected drugs by men (p < 0.0001), being a heterosexual men (p < 0.0001), and being born in South America (p < 0.0001) or sub-Saharan Africa (p = .002). Conclusion: Late presentation of HIV is still too frequent in all transmission groups in spite of a strong commitment with HIV prevention in our city. It is necessary to develop interventions that increase HIV testing and facilitate earlier entry into HIV care.Universitat Autònoma de Barcelona 22011-01-0120112011-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/112191https://dx.doi.org/urn:doi:10.1186/1742-6405-8-22reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:1121912026-06-06T12:50:31Z
dc.title.none.fl_str_mv	Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009
title	Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009
spellingShingle	Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009 García de Olalla, Patricia\|\|\|0000-0002-2293-3560 HIV infection Late presentation Epidemiology predictors Barcelona Spain
title_short	Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009
title_full	Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009
title_fullStr	Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009
title_full_unstemmed	Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009
title_sort	Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009
dc.creator.none.fl_str_mv	García de Olalla, Patricia\|\|\|0000-0002-2293-3560 Manzardo, Christian Sambeat Doménech, María Antonia Ocaña Rivera, Immaculada\|\|\|0000-0003-3699-0790 Knobel Freud, Hernando\|\|\|0000-0003-3186-6416 Humet, Victoria Domingo Pedrol, Pedro\|\|\|0000-0003-1138-5770 Ribera Pascuet, Esteban Guelar, Ana Marco, Andrés Belza, María José\|\|\|0000-0003-4816-7750 Miró, José M.\|\|\|0000-0001-8057-7755 Caylà, Joan A.\|\|\|0000-0003-3891-111X
author	García de Olalla, Patricia\|\|\|0000-0002-2293-3560
author_facet	García de Olalla, Patricia\|\|\|0000-0002-2293-3560 Manzardo, Christian Sambeat Doménech, María Antonia Ocaña Rivera, Immaculada\|\|\|0000-0003-3699-0790 Knobel Freud, Hernando\|\|\|0000-0003-3186-6416 Humet, Victoria Domingo Pedrol, Pedro\|\|\|0000-0003-1138-5770 Ribera Pascuet, Esteban Guelar, Ana Marco, Andrés Belza, María José\|\|\|0000-0003-4816-7750 Miró, José M.\|\|\|0000-0001-8057-7755 Caylà, Joan A.\|\|\|0000-0003-3891-111X
author_role	author
author2	Manzardo, Christian Sambeat Doménech, María Antonia Ocaña Rivera, Immaculada\|\|\|0000-0003-3699-0790 Knobel Freud, Hernando\|\|\|0000-0003-3186-6416 Humet, Victoria Domingo Pedrol, Pedro\|\|\|0000-0003-1138-5770 Ribera Pascuet, Esteban Guelar, Ana Marco, Andrés Belza, María José\|\|\|0000-0003-4816-7750 Miró, José M.\|\|\|0000-0001-8057-7755 Caylà, Joan A.\|\|\|0000-0003-3891-111X
author2_role	author author author author author author author author author author author author
dc.contributor.none.fl_str_mv	Universitat Autònoma de Barcelona
dc.subject.none.fl_str_mv	HIV infection Late presentation Epidemiology predictors Barcelona Spain
topic	HIV infection Late presentation Epidemiology predictors Barcelona Spain
description	Background: Early diagnosis of HIV infection can prevent morbidity and mortality as well as reduce HIV transmission. The aim of the present study was to assess prevalence, describe trends and identify factors associated with late presentation of HIV infection in Barcelona (Spain) during the period 2001-09. Methods: Demographic and epidemiological characteristics of cases reported to the Barcelona HIV surveillance system were analysed. Late presentation was defined for individuals with a CD4 count below 350 cells/ml upon HIV diagnosis or diagnosis of AIDS within 3 months of HIV diagnosis. Multivariate logistic regression were used to identify predictors of late presentation. Results: Of the 2,938 newly diagnosed HIV-infected individuals, 2,507 (85,3%) had either a CD4 cell count or an AIDS diagnosis available. A total of 1,139 (55.6%) of the 2,507 studied cases over these nine years were late presenters varying from 48% among men who have sex with men to 70% among heterosexual men. The proportion of late presentation was 62.7% in 2001-2003, 51.9% in 2004-2005, 52.6% in 2006-2007 and 52.1% in 2008-2009. A decrease over time only was observed between 2001-2003 and 2004-2005 (p = 0.001) but remained constant thereafter (p = 0.9). Independent risk factors for late presentation were older age at diagnosis (p < 0.0001), use of injected drugs by men (p < 0.0001), being a heterosexual men (p < 0.0001), and being born in South America (p < 0.0001) or sub-Saharan Africa (p = .002). Conclusion: Late presentation of HIV is still too frequent in all transmission groups in spite of a strong commitment with HIV prevention in our city. It is necessary to develop interventions that increase HIV testing and facilitate earlier entry into HIV care.
publishDate	2011
dc.date.none.fl_str_mv	2 2011-01-01 2011 2011-01-01
dc.type.none.fl_str_mv	Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv	info:eu-repo/semantics/article
format	article
dc.identifier.none.fl_str_mv	https://ddd.uab.cat/record/112191 https://dx.doi.org/urn:doi:10.1186/1742-6405-8-22
url	https://ddd.uab.cat/record/112191 https://dx.doi.org/urn:doi:10.1186/1742-6405-8-22
dc.language.none.fl_str_mv	Inglés eng
language_invalid_str_mv	Inglés
language	eng
dc.rights.none.fl_str_mv	open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv	info:eu-repo/semantics/openAccess
rights_invalid_str_mv	open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv	openAccess
dc.format.none.fl_str_mv	application/pdf
dc.source.none.fl_str_mv	reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona
instname_str	Universitat Autònoma de Barcelona
reponame_str	Dipòsit Digital de Documents de la UAB
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Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009

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